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Zosyn

Zosyn Dosage

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on October 15, 2024

Typical dosage for Zosyn

In general, Zosyn is given into the veins (IV) as a short infusion over 30 minutes. Your dose will differ if you have kidney problems.

Adults

  • Pneumonia: The typical dose is 3.375 or 4.5 grams IV every 6 hours for 7 to 14 days.
  • Other infections: The typical dose is 3.375 grams IV every 6 hours for 7 to 10 days.

Children

  • The prescriber will calculate the dose based on your child's weight. Children weighing more than 88 lbs (40 kg) who don't have kidney problems are given the adult dose.
  • Appendicitis or peritonitis
    • Age 2 to 9 months: The typical dose is 90 mg/kg IV every 8 hours.
    • Age older than 9 months: The typical dose is 112.5 mg/kg IV every 8 hours.
  • Pneumonia
    • Age 2 to 9 months: The typical dose is 90 mg/kg IV every 6 hours.
    • Age older than 9 months: The typical dose is 112.5 mg/kg IV every 6 hours.

Note: How long your infusion takes and how often you need infusions might be different depending on your situation and the healthcare facility's specific protocols.

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