Typical dosage for Zosyn
In general, Zosyn is given into the veins (IV) as a short infusion over 30 minutes. Your dose will differ if you have kidney problems.
Adults
- Pneumonia: The typical dose is 3.375 or 4.5 grams IV every 6 hours for 7 to 14 days.
- Other infections: The typical dose is 3.375 grams IV every 6 hours for 7 to 10 days.
Children
- The prescriber will calculate the dose based on your child's weight. Children weighing more than 88 lbs (40 kg) who don't have kidney problems are given the adult dose.
- Appendicitis or peritonitis
- Age 2 to 9 months: The typical dose is 90 mg/kg IV every 8 hours.
- Age older than 9 months: The typical dose is 112.5 mg/kg IV every 8 hours.
- Pneumonia
- Age 2 to 9 months: The typical dose is 90 mg/kg IV every 6 hours.
- Age older than 9 months: The typical dose is 112.5 mg/kg IV every 6 hours.
Note: How long your infusion takes and how often you need infusions might be different depending on your situation and the healthcare facility's specific protocols.


