The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Diarrhea (11%)
- Headache (8%)
- Constipation (8%)
- Nausea (7%)
- Trouble sleeping (7%)
- Rash (4%)
- Itching (3%)
- Vomiting (3%)
- Upset stomach (3%)
Less Common Side Effects
- Stomach pain
- Muscle pain
- Joint pain
- Fever
- Chills
- Low blood pressure
- Fungal infection
Zosyn serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction or serious skin reaction: hives; rash; blisters; skin reddening; peeling skin; swelling of the face, lips, or tongue; trouble breathing
- Side effects related to the nervous system: hallucinations (seeing or hearing things that aren't real), seizures, sudden and brief involuntary movements or twitching
- Clostridioides difficile-related diarrhea: fever, stomach pain or cramps, foul-smelling diarrhea, frequent bowel movements (up to 15 times per day)
Source: DailyMed
The following Zosyn side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Less common
Bladder pain
bloating or swelling of the face, arms, hands, lower legs, or feet
blurred vision
burning upper abdominal or stomach pain
changes in urination
confusion
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fever or sweating
headache
lower back or side pain
nausea or vomiting
pain, tenderness, or swelling of the foot or leg
pain, warmth, or burning in the fingers, toes, and legs
problems with vision or hearing
skin rash
slow or fast heartbeat
troubled breathing
Rare
Agitation
bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
bone pain
bruising
chills
cold sweats
deep or fast breathing with dizziness
diarrhea, watery and severe, which may also be bloody
drowsiness
hostility
itching of the vagina or genital area
lethargy
muscle pain, cramps, stiffness, or twitching
nightmares
numbness or tingling in the hands, feet, or lips
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
sores, ulcers, or white spots on the lips, tongue, or inside the mouth
stomach cramps, pain, or tenderness
swollen glands
temporary blindness
thick, white vaginal discharge with no odor or with a mild odor
total body jerking
unexplained weight loss
unusual bleeding or bruising
Incidence not known
Back or leg pain
blistering, peeling, or loosening of the skin
high fever
joint or muscle pain
loss of bladder control
muscle spasm or jerking of all extremities
red skin lesions, often with a purple center
seizures
sudden loss of consciousness
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Acid or sour stomach
cracks in the skin at the corners of the mouth
hiccup
irritation and redness of the skin
Rare
Body aches or pain
change in taste or bad unusual or unpleasant (after) taste
feeling of constant movement of self or surroundings
sensation of spinning
severe sleepiness
voice changes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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