The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Zoryve (roflumilast) 0.05% cream:
- Upper respiratory tract infection (4%)
- Diarrhea (3%)
- Vomiting (2%)
- Runny nose (2%)
Zoryve (roflumilast) 0.15% cream:
- Headache (3%)
- Nausea (2%)
Zoryve (roflumilast) 0.30% cream:
- Diarrhea (3%)
- Headache (2%)
Zoryve (roflumilast) 0.30% foam:
- Headache (3%)
- Diarrhea (3%)
- Nausea (2%)
Less Common Side Effects
- Skin pain where the medication is applied
- Trouble sleeping
- Nose and throat inflammation
- Pink eye
Source: Prescribing information
The following Zoryve side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
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