Skip to main content
Zelsuvmi

Zelsuvmi Side Effects

Ella Bolin, PharmD CandidateCydnee Ng, PharmD
Reviewed by Ella Bolin, PharmD Candidate, Cydnee Ng, PharmD, Daisy Chau, PharmD
Last reviewed on August 29, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Pain (such as burning or stinging, 19%)
  • Redness (12%)
  • Itching (6%)
  • Peeling or flaking (5%)
  • Itchy, dry skin rash (5%)

Less Common Side Effects

  • Swelling
  • Fever
  • Open wound at the skin surface
  • Skin discoloration
  • Blistering
  • Vomiting
  • Other irritation at the application site
  • Infection at the application site
  • Upper respiratory tract infection

Zelsuvmi serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Allergic skin reaction: pain, itching, swelling, or redness at the application site that lasts longer than 24 hours
When do Zelsuvmi possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Pain after applying
Skin redness after applying
Flaking or crusting
Swelling

Source: FDA

The following Zelsuvmi side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Change in skin color
  • Irritation at application site
GoodRx icon

Other Zelsuvmi articles

Was this page helpful?