Voriconazole Dosage

Voriconazole is available as a tablet and oral suspension that are taken by mouth (oral) and an injection that's given as an infusion through the veins (IV).

For serious infections, your care team will give you Voriconazole IV infusion in a hospital setting for at least a week before switching you to the oral forms of Voriconazole.

Adults and children ages 15 years or older:

• Aspergillosis, scedosporiosis, and fusariosis: The typical starting dose is 6 mg/kg IV every 12 hours for two doses, then 4 mg/kg IV every 12 hours. Once your condition improves and you're able to take medications by mouth, your care team might switch you to oral Voriconazole 200 mg by mouth every 12 hours.
• Candidiasis in the bloodstream or deep tissue: The typical starting dose is 6 mg/kg IV every 12 hours for two doses, then 3–4 mg/kg IV every 12 hours. Once your condition improves and you're able to take medications by mouth, your care team might switch you to oral Voriconazole 200 mg by mouth every 12 hours.
• Candidiasis in the esophagus: The typical dose is 200 mg by mouth every 12 hours.

Children (ages 2 to under 12 years, and ages 12 to under 15 years who weigh less than 50 kg):

• Aspergillosis, candidiasis in the bloodstream or deep tissue, scedosporiosis, and fusariosis: The typical starting dose is 9 mg/kg IV every 12 hours for two doses, then 8 mg/kg IV every 12 hours. Once your child's condition improves and they're able to take medications by mouth, their pediatrician might switch them to oral Voriconazole 9 mg/kg (up to 350 mg) by mouth every 12 hours.
• Candidiasis in the esophagus: The typical dose is 9 mg/kg (up to 350 mg) by mouth every 12 hours.

Your prescriber will adjust your dose based on different factors, such as your liver health and how well Voriconazole is treating your infection.