Key takeaways:
Without insurance, a 100 mg/mL One-Press Tremfya (guselkumab) injector costs an average of $19634.80.
Most insurance plans cover Tremfya. But prior authorization and step therapy are usually required before the medication is covered.
You can reduce the cost of Tremfya with a manufacturer’s copay savings card (if you have commercial insurance) or through a patient assistance program if you qualify.
Save on related medications
Tremfya (guselkumab) is a prescription biologic medication that’s used to treat several inflammatory conditions, from Crohn’s disease to psoriatic arthritis. It’s often used long term, so understanding what you’ll pay is an important part of planning your treatment.
Tremfya is available as a self-administered injection or, for some conditions, an IV infusion given in a healthcare setting. Your out-of-pocket costs can vary depending on your insurance coverage, dosage, and where you receive the medication.
Fortunately, there are several programs that may help lower your out-of-pocket costs. Here’s what you should know.
How much does Tremfya cost?
As of March 2025, the manufacturer’s list price is $14,566 for a single Tremfya injection or IV infusion. But most people don’t pay this price because of pharmacy markups and other factors. Tremfya is typically administered every 4 to 8 weeks (1 to 2 months).
It’s important to note that Tremfya is a biologic medication, meaning that it’s made using living systems. Biologics don’t have generics. Instead, they have biosimilars, which closely resemble the brand-name (reference) product but often have a lower cost. No biosimilar for Tremfya is available in the U.S.
Here are some average cash prices for Tremfya:
Which factors affect the cost of Tremfya?
Without insurance, what you pay for Tremfya depends on several factors, including your:
Pharmacy: Prices can vary by pharmacy. And because Tremfya is a specialty medication, only certain pharmacies may carry it.
How you receive it: Tremfya can be injected at home or given as an IV infusion in a healthcare setting. An infusion may come with additional administration or facility charges.
Location: Medication prices can vary depending on where you live and fill your prescription.
Dosage and treatment schedule: How much Tremfya you receive and how often you receive it can affect your overall treatment costs. Some conditions require more frequent doses when you first start treatment.
Fill quantity: The price per dose may differ depending on how many doses you receive at one time. In some cases, getting more than 1 dose per fill may lower the cost per dose.
Does insurance cover Tremfya?
Most health insurance plans cover Tremfya. If you have insurance, review your plan’s summary of benefits and coverage and formulary (list of covered medications) to determine whether Tremfya is covered. If it is not, contact your plan and ask about your coverage options. You can also discuss alternatives with your prescriber or pharmacist.
For you to get coverage for Tremfya, most health insurance plans require prior authorization. This means your prescriber must provide documentation that Tremfya is medically necessary. And step therapy (when you need to try other medications first) is most common for people covered by Medicaid, commercial plans not purchased through an Affordable Care Act (ACA) marketplace, and ACA plans.
How different insurance plans cover Tremfya
The following charts show the likelihood of having coverage for different self-administration methods of Tremfya with various types of insurance plans. They also show the likelihood of needing to obtain a prior authorization and complete step therapy.
Insurance type | Enrollees covered for Tremfya One-Press injector, 100 mg / 1 mL | Enrollees required to get prior authorization | Enrollees required to do step therapy |
|---|---|---|---|
90.7% | 86.6% | 80% | |
Commercial plans (excluding ACA plans) | 98.7% | 88.1% | 85.5% |
Medicare (Medicare Advantage and Part D plans) | 72.3% | 69% | 66.3% |
Medicaid, including state-run and managed care plans | 99.6% | 93.7% | 67.8% |
Source: Managed Markets Insight & Technology, LLC™, as of August 8, 2025 (See methodology below).
Insurance type | Enrollees covered for Tremfya syringe, 100 mg / 1 mL | Enrollees required to get prior authorization | Enrollees required to do step therapy |
|---|---|---|---|
ACA plans | 90.7% | 86.6% | 79.9% |
Commercial plans (excluding ACA plans) | 98.7% | 87.7% | 85.1% |
Medicare (Medicare Advantage and Part D plans) | 72.3% | 69% | 65.9% |
Medicaid, including state-run and managed care plans | 99.6% | 93.7% | 67.8% |
Source: Managed Markets Insight & Technology, LLC™, as of August 8, 2025 (See methodology below).
Insurance type | Enrollees covered for Tremfya syringe, 200 mg / 2 mL | Enrollees required to get prior authorization | Enrollees required to do step therapy |
|---|---|---|---|
ACA plans | 90.2% | 86.8% | 50.5% |
Commercial plans (excluding ACA plans) | 98.1% | 87.7% | 59.7% |
Medicare (Medicare Advantage and Part D plans) | 71.8% | 68.5% | 32% |
Medicaid, including state-run and managed care plans | 99.5% | 87.7% | 41.3% |
Source: Managed Markets Insight & Technology, LLC™, as of August 8, 2025 (See methodology below).
What to do if Tremfya isn’t covered by your insurance
If your insurance doesn’t cover Tremfya, you still have options:
See if you’re eligible for a patient assistance program.
Ask your prescriber about less costly options that meet your needs. This could mean switching to another brand-name medication that costs less or a medication that has a generic or biosimilar option available. (Tremfya has no biosimilars approved in the U.S.)
Request a formulary exception from your insurance company. If your request is denied, you have the right to file an appeal with your plan.
When it’s time for open enrollment, compare health insurance plans to find one that provides coverage for this medication.
Specialty pharmacies often have designated staff members who can help you navigate insurance requirements, as well as savings programs and eligibility.
Ways to save on Tremfya
Whether or not you have insurance, there are ways to reduce the cost of Tremfya. Here are three options.
1. See if you qualify for a copay savings card
Johnson & Johnson, the manufacturer of Tremfya, offers several support solutions to reduce your out-of-pocket costs. If you have commercial insurance, you may be able to benefit from a manufacturer’s copay savings card. You could pay as little as $0 through the Tremfya withMe Savings Program, which can help you pay for out-of-pocket costs toward your copays, coinsurance, and deductible.
If you have a Tremfya IV infusion, there’s also support for administration and lab tests with a $2,000 maximum annual benefit. If you’re enrolled in the Tremfya withMe Savings Program, your discount doesn’t get processed or applied at the pharmacy, and you pay out of pocket, then you can request a rebate for your out-of-pocket costs. You can add eligible administration and lab-test costs to the rebate request if you received a Tremfya infusion.
If your insurance participates in copay adjustment through copay accumulator or copay maximizer programs, you may be subject to savings limits per dose, per month, and annually as a way to ensure the savings accrue to you and not your health plan.
You don’t qualify for the copay savings card if you have government insurance, such as Medicare, Medicaid, or Tricare, or rely on a state patient assistance program or state pharmaceutical assistance program.
You can sign up for financial support by identifying yourself as a patient and choosing the condition you need Tremfya to treat. You’ll be guided to the manufacturer program that best fits your needs. If you have questions, you can call 1-833-948-4631 for assistance.
2. See if you qualify for a patient assistance program
The Johnson & Johnson Patient Assistance Program helps people living in the U.S., including U.S. territories, receive free Tremfya whether you have insurance or not. If you meet income requirements and find your medication unaffordable, you may qualify for this program. Medicare Part D enrollees are eligible if they spend more than 4% of their gross annual household income on prescriptions and show that they are not eligible for the Extra Help low-income subsidy.
You may also be able to get help through other patient assistance programs. If you’re covered by Medicare, the Patient Access Network (PAN) Foundation offers grants to pay treatment costs for people who have a demonstrated need for financial support. The PAN Foundation has an inflammatory bowel disease fund that will help cover copays and other costs for Tremfya. At publication time, this fund was not accepting new or renewal enrollees, but you can join the wait list.
3. Tap into your HSA, FSA, or HRA
Consider using a flexible spending account (FSA), a health savings account (HSA), or a health reimbursement arrangement (HRA) to pay for your medication. You can enjoy multiple tax benefits when funds from an FSA, an HSA, or an HRA are used to pay for qualified healthcare expenses. This can reduce your out-of-pocket costs through tax savings. But be sure to review your account’s contribution limits, rollover limits, and eligible expenses.
The bottom line
Tremfya (guselkumab) is an FDA-approved medication for managing certain types of plaque psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. As of March 2025, the manufacturer’s list price is $14,566 for a single Tremfya injection or IV infusion. There’s no biosimilar version of this medication approved in the U.S.
If you have commercial insurance and use the manufacturer’s copay savings card, your out-of-pocket costs could be as little as $0. If you have no insurance, financial hardship, or Medicare Part D and you meet certain income requirements, then you may be able to get free medication through the manufacturer’s patient assistance program.
Why trust our experts?
Methodology
We obtained national prescription coverage data for each medication from Managed Markets Insight & Technology (MMIT). The data reflects health insurance coverage as of August 2025.
We calculated the **percentage of enrollees in plans that cover each medication** by dividing the number of enrollees covered for the medication within a specific insurance channel (e.g., ACA, Medicare, Medicaid) by the total number of enrollees in all plans within that channel.
We determined the **percentage of enrollees in plans with a prior authorization **requirement by calculating the proportion of enrollees in plans that required prior authorization for the medication within each channel.
Finally, we measured the **percentage of enrollees in plans with a step therapy** requirement by calculating the proportion of enrollees in plans that imposed step therapy requirements for the medication in each channel.
These estimates, derived from national MMIT coverage data, provide insight into health insurance coverage for each medication. They take into account restrictions such as prior authorization, step therapy, and quantity limits. The percentages are expressed relative to the total number of enrollees covered by various insurance channels, including ACA plans, commercial (excluding ACA) plans, Medicare, and Medicaid (both state-run and managed care plans).
References
J&J withMe. (2026). Savings program rebate request—instructions. Johnson & Johnson.
Johnson & Johnson Patient Assistance Program. (2026). Quick reference guide.
Medicaid.gov. (n.d.). Managed care. Centers for Medicare & Medicaid Services.
Patient Advocate Foundation. (n.d.). List of all TotalAssist Funds.
Patient Advocate Foundation. (n.d.). TotalAssist is here to help with your healthcare costs.
Tremfya withMe. (2025). Get free, personalized support to help make it easier to start and stay on treatment. Johnson & Johnson.
Tremfya withMe. (2025). Medical benefit rebate form. Johnson & Johnson.
Tremfya withMe. (2025). Tremfya withMe savings program. Johnson & Johnson.
Tremfya withMe. (2026). Commercial or private insurance. Johnson & Johnson.
Tremfya withMe. (2026). Paying for Tremfya. Johnson & Johnson.
Tremfya withMe. (2026). Sign up for support today! Johnson & Johnson.
