First Liquid Levothyroxine for Hypothyroidism Now Available in Pharmacies

The first liquid levothyroxine, Tirosint-Sol, has finally made its way to pharmacies! Approved back in 2016,  the new medication is now available to patients with hypothyroidism who prefer a liquid (instead of tablet) formulation.

What is Tirosint-Sol?

Tirosint-Sol (levothyroxine) is approved to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormones. Hypothyroidism can cause symptoms like tiredness, weight gain, depression, and forgetfulness.

In the past, those with hypothyroidism had to take tablet or capsule medications like Synthroid, generic levothyroxine, and Tirosint. However, with the approval of the new liquid formulation, more patients, like those who are unable to swallow a tablet or capsule, have access to hypothyroidism treatment.

How should I take Tirosint-Sol?

Tirosint-Sol should be taken once daily on an empty stomach, and 30 minutes to 1 hour before breakfast. The liquid can be diluted in a glass of water, or squeezed directly onto a spoon or in the mouth for immediate consumption. It is both gluten- and lactose-free, and will be absorbed into your system faster than tablets.

Tirosint-Sol is available in the following strengths:

• 13 mcg/ml

• 25 mcg/ml

• 50 mcg/ml

• 75 mcg/ml

• 88 mcg/ml

• 100 mcg/ml

• 112 mcg/ml

• 125 mcg/ml

• 137 mcg/ml

• 150 mcg/ml

• 175 mcg/ml

• 200 mcg/ml

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If you start taking Tirosint-Sol, your doctor will likely perform periodic blood tests to check various hormone levels and ensure that the medication is working.

How to save on Tirosint-Sol

There are ways to save on Tirosint-Sol, which is only available as a brand-name medication. GoodRx can help you navigate between patient assistance programs and copay savings cards to save money on your prescription.

• Save with patient assistance programs. If you’re uninsured or underinsured, you may be eligible for Tirosint-Sol's patient assistance program, which offers the medication free of cost.

• Save with a copay savings card. If you have commercial insurance, you may be eligible to pay as little as $25 for Tirosint-Sol using a savings card from the manufacturer.

Why trust our experts?

Written by:

Ronilee Shye, PharmD, BCGP, BCACP, CDE

Roni is an expert in clinical pharmacy and patient care. She received her doctorate in pharmacy from Duquesne University in Pittsburgh, Pennsylvania; is board-certified in geriatrics and ambulatory care pharmacy; and is licensed to practice pharmacy in Ohio, Pennsylvania, and Florida.

Edited by:

Benita Lee, MPH

Benita Lee, MPH, is director of content and operations at GoodRx and contributes to content strategy and process management across editorial and product initiatives. She is passionate about building collaborative teams and has a deep interest in using research to improve health outcomes in innovative and sustainable ways.

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