The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Skin redness (71%)
- Whitish or pale coloring of skin (12%)
- Swelling (12%)
Less Common Side Effects
- Itching
- Rash
- Skin discoloration
Synera serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe blood problem (methemoglobinemia): seizures, loss of consciousness, fast heart beat, trouble breathing, feeling dizzy or faint, feeling tired, skin color turning blue or pale
- Serious allergic reactions: swelling of the face, difficulty breathing, trouble speaking, throat tightening up, red and itchy rash, lightheadedness, clammy skin
Source: DailyMed
The following Synera side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Flushing or redness of the skin
swelling
unusually warm skin
Less common
Blistering, burning, crusting, dryness, or flaking of the skin
change in the color of treated skin
itching, scaling, severe redness, soreness, or swelling of the skin
rash
Rare
Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chills
fainting or loss of consciousness
fast or irregular breathing
hives or welts
hoarseness
lower back or side pain
painful or difficult urination
swelling of the eyes or eyelids
tightness in the chest
trouble with breathing
Incidence not known
Blurred vision
chest pain or discomfort
cold, clammy, or pale skin
confusion
difficulty with breathing
difficulty with swallowing
dizziness
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fast, slow, or irregular heartbeat
feelings of coldness, heat, or numbness
irregular, fast or slow, or shallow breathing
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
no breathing
noisy breathing
pale or blue lips, fingernails, or skin
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
seizures
shakiness in the legs, arms, hands, or feet
slow heart rate
sweating
trembling or shaking of the hands or feet
twitching
unusual tiredness or weakness
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Change in consciousness
fast, pounding, or irregular heartbeat or pulse
no blood pressure or pulse
stopping of the heart
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Continuing ringing or buzzing or other unexplained noise in the ears
double vision
drowsiness
false or unusual sense of well-being
fear
hearing loss
nervousness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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