How Much Is Spironolactone Without Insurance?

Spironolactone (Aldactone, CaroSpir) is a prescription-only, potassium-sparing diuretic (water pill). It is FDA approved to treat high blood pressure, heart failure, and edema (swelling from fluid buildup), often when it’s caused by liver or kidney conditions. Spironolactone also helps with treating hyperaldosteronism, a condition in which the body overproduces the hormone aldosterone.

While it’s not approved for these conditions, spironolactone is also often prescribed off-label to treat acne and polycystic ovary syndrome (PCOS).

How much you’ll pay for spironolactone depends on factors like your pharmacy and your prescribed dose and medication form. Many insurance plans cover the medication, but if you're paying out of pocket, GoodRx coupons can help you save.

How much does spironolactone cost?

Spironolactone is available in tablet form in doses of 25 mg, 50 mg, and 100 mg. It also comes as an oral suspension in a 25 mg/5 mL dose. The recommended spironolactone dosage for adults varies based on the condition being treated and which form of the medication is prescribed. 

Without insurance, discounts, or coupons, 30 tablets of 25 mg spironolactone cost an average of $10.54. On average, the same dose and quantity of brand-name Aldactone costs $122.20. Meanwhile, a 118 mL bottle of the 25 mg/5 mL oral suspension runs about $465.90 on average.

The table below provides the average retail price for various quantities, forms, and doses of generic and brand-name versions of spironolactone.

What factors affect the cost of spironolactone?

How much you’ll pay for your spironolactone prescription will depend on several factors, including:

• Location: Where you live can impact the price you pay for spironolactone. According to GoodRx research, cities like Atlanta and Denver tend to have lower-than-average medication prices, while areas like New Orleans and Milwaukee often have higher prices.

• Brand-name versus generic version: Generic spironolactone generally costs less than its brand-name counterparts, Aldactone and CaroSpir. For the oral suspension, you’ll likely pay nearly double the price for brand-name CaroSpir compared to the generic.

• Pharmacy: Prices for spironolactone can vary significantly between pharmacies, even ones in the same area. One pharmacy might charge more than another just down the street.

• Insurance status: If you have insurance, your out-of-pocket costs for spironolactone, including any deductibles, copays, or coinsurance, will determine the final price you’ll pay.

• Dosage and form: Your spironolactone dose can impact the price of your prescription, with a higher dose likely being more costly. In addition, the tablet form is usually more affordable than the oral suspension. 

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Spironolactone

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$5.46

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Does insurance cover spironolactone?

Most health insurance plans, including Affordable Care Act (ACA) and commercial plans, typically cover spironolactone. Medicare plans usually cover spironolactone without restrictions such as a prior authorization or step therapy. Medicaid plans cover spironolactone for nearly all enrollees, though a small percentage may need a prior authorization. 

To learn about coverage details and out-of-pocket costs, you can start by checking your plan’s formulary to see if it includes spironolactone. You can also reach out to a plan representative to ask about any additional steps you need to take to get coverage.

How different insurance plans cover spironolactone

The table below outlines the likelihood of having coverage for spironolactone, along with prior authorization or step therapy requirements, across various insurance plans.

Source: Managed Markets Insight & Technology, LLC™, as of December 13, 2024. (See methodology below.)

If your insurer does not cover spironolactone, you have a few options:

• Check if your plan covers a brand-name version of spironolactone instead.

• Discuss alternative medications that your insurance might cover with your healthcare professional.

• Request a formulary exception for spironolactone from your insurance plan.

• If you request an exception and it’s denied, consider filing an appeal.

• During the next open enrollment period, explore other insurance plans to see if you can find one that better aligns with your coverage needs.

Ways to save on spironolactone

There are a few ways you can reduce your out-of-pocket cost for spironolactone, whether you have insurance or not. Here are five possible ways to save.

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• Health savings account (HSA) benefits: Using your HSA to pay for prescription medications like spironolactone allows you to take advantage of tax savings.

• Does spironolactone improve hair loss? Here’s what the research shows. 

• Some spironolactone interactions can increase the risk of side effects. Here’s a look at substances to avoid and how they may interact with spironolactone.

1. Download a GoodRx coupon

With a free GoodRx coupon, you may be able to substantially lower the cost of your spironolactone prescription. Many pharmacies accept GoodRx coupons, and you can use the price comparison tool on the website or app to help you find the best prices in your area.

The table below highlights how much you might pay for various doses and forms of generic and brand-name spironolactone when using a GoodRx coupon.

To get your free GoodRx coupon:

• Visit www.goodrx.com or download the GoodRx app on your phone.

• Search for "spironolactone" and choose either the brand-name or generic version.

• Input your prescribed dose and quantity. 

• Click "Find the lowest prices" or press enter.

• Select if you want to receive your coupon via text or email, or print it out.

• Show the coupon at your pharmacy when you drop off your prescription to avoid delays.

2. Try a copay savings program

Eligible individuals can lower their out-of-pocket costs for CaroSpir, the liquid form of spironolactone, through CMP’s EasyPay Copay Card program. This program offers up to $75 off a 30-day prescription or $225 off a 90-day prescription of CaroSpir. 

This offer is only valid in the U.S. To qualify, you must be at least 18 years old and be prescribed brand-name CaroSpir. The program is available to insured individuals and to those paying cash. The savings apply to both new prescriptions and refills.

3. Request a larger quantity

Ask your healthcare professional to prescribe you a 90-day supply of spironolactone instead of a 30-day supply to find out if you can save. Filling a larger supply could reduce your overall costs and your trips to the pharmacy, saving you both time and money. 

If you have insurance that covers spironolactone, check for discounts through your plan’s mail-order pharmacy.

5. Use a tax-advantaged account

If you have a health savings account (HSA) or a flexible spending account (FSA), you can use the tax-free money in your account to pay for your spironolactone prescription. Keep in mind that FSA funds must be used by the end of the plan year, while HSA funds roll over and can be used at any time.

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Written by:

DeShena Woodard, BSN, RN

DeShena Woodard, BSN, RN, is a Texas-based registered nurse, freelance writer, financial freedom coach, and certified life coach. Writing about personal finance for more than 3 years, her advice has been featured on Yahoo Finance, Business Insider, NerdWallet, Debt.com, GoBankingRates, the Balance, and also on her own website, ExtravagantlyBroke.com.

Edited by:

Charlene Rhinehart, CPA

Charlene Rhinehart, CPA, is a personal finance editor at GoodRx. She has been a certified public accountant for over a decade.

Reviewed by:

Joshua Murdock, PharmD, BCBBS

Joshua Murdock, PharmD, BCBBS, is a licensed pharmacist in Arizona, Colorado, and Rhode Island. He has worked in the pharmacy industry for more than 10 years and currently serves as a pharmacy editor for GoodRx.

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Methodology

We obtained national prescription coverage data for each medication from Managed Markets Insight & Technology (MMIT). The data reflect health insurance coverage as of December 2024. 

We calculated the percentage of enrollees in plans that cover each medication by dividing the number of enrollees covered for the medication within a specific insurance channel (e.g., ACA, Medicare, Medicaid) by the total number of enrollees in all plans within that channel. 

We determined the percentage of enrollees in plans with a prior authorization requirement by calculating the proportion of enrollees in plans that required prior authorization for the medication within each channel. 

Finally, we measured the percentage of enrollees in plans with a step therapy requirement by calculating the proportion of enrollees in plans that imposed step therapy requirements for the medication in each channel. 

These estimates, derived from national MMIT coverage data, provide insight into health insurance coverage for each medication. They take into account restrictions such as prior authorization, step therapy, and quantity limits. The percentages are expressed relative to the total number of enrollees covered by various insurance channels, including ACA plans, commercial (excluding ACA) plans, Medicare, and Medicaid (both state-run and managed care plans).