The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Infantile-onset SMA (affects infants)
- Lower respiratory infection (55%)
- Constipation (35%)
- Teething (18%)
- Urinary tract infection (9%)
- Stuffy nose (8%)
- Ear infection (6%)
- Passing gas (5%)
- Weight loss (5%)
Later-onset SMA (affects children and adults)
- Fever (43%)
- Headache (29%)
- Vomiting (29%)
- Back pain (25%)
- Nosebleed (7%)
- Falls (5%)
- Stuffy nose (5%)
- Seasonal allergy (5%)
Spinraza serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious bleeds: bleeding that's difficult to stop, bloody or black-colored stool, vomiting or coughing up blood, dizziness, pale skin
- Kidney damage: low urine amount, swelling in legs or feet, shortness of breath, tiredness, confusion, nausea, weakness, irregular heartbeat, headache, or itchiness
- Atelectasis (collapsed lung): trouble breathing, fast heart rate, cough, chest pain, or skin and lips turning blue
Source: DailyMed
The following Spinraza side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
- Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Back pain
- Constipation
- Fever
- Headache
- Vomiting
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