Key takeaways:
Sotyktu (deucravacitinib) is a brand-name medication that treats plaque psoriasis. The average cost of a 1-month supply of Sotyktu without insurance is $9254.30.
Many insurance plans cover Sotyktu. But it’s common for insurance providers to require the completion of prior authorization or step therapy.
There are ways to save on Sotyktu. If you have commercial insurance, you could pay as little as $0 a month with a manufacturer copay savings card. A patient assistance program is also available.
Save on related medications
When it comes to managing plaque psoriasis, there are many treatment options. One medication your prescriber may discuss with you is Sotyktu (deucravacitinib). This oral medication helps reduce inflammation that contributes to psoriasis symptoms.
When you’re prescribed a new medication, cost is often top of mind. Office visits and prescription prices can quickly add up, especially if you’re uninsured or underinsured. So if you’re wondering how much Sotyktu costs without insurance, you’re not alone.
Below, you’ll find details about Sotyktu’s average retail cost and ways you can save on the medication with or without insurance.
How much does Sotyktu cost without insurance?
Sotyktu comes as a 6 mg tablet that you take by mouth once a day. On average, a 30-day supply of Sotyktu costs about $9254.30 without insurance. And the average retail cost for a 90-day supply is $28985.00.
Sotyktu is a brand-name medication. There isn’t a generic version available yet. It’s also the only medication in its class.
What factors affect the cost of Sotyktu?
There are many factors that affect that cost of Sotyktu, including:
Insurance: If you have insurance, how much you pay for Sotyktu will depend on your plan’s cost-sharing requirements. You may have out-of-pockets costs such as deductibles, copays, or coinsurance amounts.
Pharmacy: Sotyktu is a limited distribution drug. This means that only certain pharmacies, namely specialty pharmacies, can fill prescriptions for it. The price you pay may depend on which pharmacy you use — and if it’s preferred by your insurance plan, if applicable.
Location: Medication costs can also be affected by where you live. For instance, people in Atlanta generally pay less for prescription medications than people in New York City.
Discounts: You may be able to lower the cost of Sotyktu by using a manufacturer copay savings card or a patient assistance program.
Does insurance cover Sotyktu?
Insurance coverage for Sotyktu varies among plans.
Over 95% of commercial and Medicaid plans cover Sotyktu. But it’s very common for providers of these plans to require prior authorization before they’ll cover it. To get prior authorization, your prescriber will need to provide extra information about why you need the medication. Many commercial and Medicaid plans also commonly require enrollees to complete step therapy (try other medications first).
About 78% of Affordable Care Act (ACA) marketplace plans cover Sotyktu. Medicare coverage is more limited, with an estimated 44% of plans covering it. But it’s common for both ACA and Medicare plans to require prior authorization and/or step therapy.
You can determine if your plan covers Sotyktu by referring to your summary of benefits and coverage and formulary (list of covered medications). If you’re unsure, call the member services number on your prescription insurance card for more details.
How different insurance plans cover Sotyktu
The table below highlights how often plans across different insurance types cover Sotyktu. It also shows how likely they are to require prior authorization or step therapy.
Insurance type | Enrollees covered for Sotyktu | Enrollees required to get prior authorization | Enrollees required to do step therapy |
|---|---|---|---|
77.6% | 74% | 65% | |
Commercial plans (excluding ACA plans) | 95.5% | 75.6% | 70.3% |
Medicare (Medicare Advantage and Part D plans) | 44% | 44% | 41.4% |
Medicaid, including state-run and managed care plans | 99.9% | 99.5% | 63.7% |
Source: Managed Markets Insight & Technology, LLC™, as of January 10, 2026. (See methodology below.)
If your insurance doesn’t cover Sotyktu, try these options:
See if you qualify for Sotyktu’s manufacturer copay savings card or patient assistance program (discussed below).
Request a formulary exception from your insurance company. If your request is denied, you have the right to appeal the decision to seek coverage.
Discuss alternatives with your prescriber. There are other plaque psoriasis medications that may provide similar benefits to Sotyktu. And your plan may offer better coverage for one of them.
When it’s time for open enrollment, compare different health insurance plans to find one that provides better coverage for what you need.
Ways to save on Sotyktu
There are ways to save on Sotyktu, with or without insurance. Below are four options to look into.
Good to know: Your specialty pharmacy team can help you apply for Sotyktu savings opportunities. Be sure to ask them if and how you can take advantage of the options discussed below.
1. See if you qualify for a copay savings card
If you have commercial insurance, you may be able to pay as little as $0 per month for Sotyktu with a manufacturer copay savings card.
To qualify for the Sotyktu copay savings card, you must:
Have commercial insurance that covers part of your Sotyktu prescription
Not have or be eligible for government-funded insurance, such as Medicare, Medicaid, or Tricare
Be at least age 18
Live in the U.S. or a U.S. territory
You can apply for the Sotyktu copay savings card online. If you have questions, call 1-888-768-9588.
2. Check if you’re eligible for a patient assistance program
If you’re uninsured or underinsured, you may be able to get Sotyktu for free through the manufacturer’s patient assistance program.
You may be eligible for this program if you:
Live in the U.S. or a U.S. territory
Are being treated by a U.S.-licensed healthcare professional
Have a valid prescription for Sotyktu for an FDA-approved use
Are uninsured or underinsured and don’t qualify for Medicaid
Meet certain income requirements and are able to submit proof of income
You can qualify for this program if you have Medicare, as long as you’re not eligible for the Extra Help program.
You can apply for Sotyktu’s patient assistance program online, or by calling 1-800-736-0003 and having the application form mailed to you. Your prescriber will also need to complete a portion of the application form. As mentioned, your specialty pharmacy can help you with this process.
3. Ask about 90-day supplies
Sometimes, pharmacies and insurance providers offer discounts when you fill a 3-month supply of your medication. This can help lower your monthly costs over time.
What’s more, your insurance plan may offer a lower copay or coinsurance if you fill your Sotyktu prescription with their preferred specialty mail-order pharmacy. Speak with your specialty pharmacy and insurance provider to see if you’re able to save with these options.
4. Tap into your HSA, FSA, or HRA
If you have a health savings account (HSA), a flexible spending account (FSA), or a health reimbursement arrangement (HRA), you can use those pretax dollars to pay for Sotyktu. This helps lower your costs through tax savings.
Be sure to review your HSA, FSA, or HRA details. FSA funds have an expiration date. But HSA funds roll over and can be saved for later. HRA funds may or may not roll over, depending on your plan.
The bottom line
The average cost of a 1-month supply of Sotyktu (deucravacitinib) without insurance is $9254.30. Many insurance plans cover this medication. But it’s common for plans to require prior authorization or the completion of step therapy first.
If you have commercial insurance, you may be able to pay as low as $0 per month for Sotyktu with a manufacturer copay savings card. Or if you’re uninsured or underinsured, you may qualify for Sotyktu’s patient assistance program, which offers the medication free of charge to eligible applicants. Your specialty pharmacy can help you explore all the ways that you can save on Sotyktu.
Why trust our experts?
Methodology
We obtained national prescription coverage data for each medication from Managed Markets Insight & Technology (MMIT). The data reflects health insurance coverage as of January 2026.
We calculated the percentage of enrollees in plans that cover each medication by dividing the number of enrollees covered for the medication within a specific insurance channel (e.g., ACA, Medicare, Medicaid) by the total number of enrollees in all plans within that channel.
We determined the percentage of enrollees in plans with a prior authorization requirement by calculating the proportion of enrollees in plans that required prior authorization for the medication within each channel.
Finally, we measured the percentage of enrollees in plans with a step therapy requirement by calculating the proportion of enrollees in plans that imposed step therapy requirements for the medication in each channel.
These estimates, derived from national MMIT coverage data, provide insight into health insurance coverage for each medication. They take into account restrictions such as prior authorization, step therapy, and quantity limits. The percentages are expressed relative to the total number of enrollees covered by various insurance channels, including ACA plans, commercial (excluding ACA) plans, Medicare, and Medicaid (both state-run and managed care plans).
References
Bristol-Myers Squibb Patient Assistance Foundation. (n.d.). Eligibility requirements.
Bristol-Myers Squibb Patient Assistance Foundation. (n.d.). How do I apply?
E.R. Squibb & Sons. (2022). Sotyktu - deucravacitinib tablet, film coated [package insert]. DailyMed.
Medicaid.gov. (n.d.). Managed care.
Sotyktu. (n.d.). Sign up for Sotyktu co-pay card. Bristol-Myers Squibb.
Sotyktu. (n.d.). Sotyktu 360 Support terms & conditions. Bristol-Myers Squibb.
Sotyktu. (2025). Specialty pharmacy resource. Bristol-Myers Squibb.
