provider image
Welcome! You’re in GoodRx for healthcare professionals. Now, you’ll enjoy a streamlined experience created specifically for healthcare professionals.
Skip to main content
Simethicone Coupon - Simethicone 80mg chewable tablet

simethicone

Generic Gas-X
Used for Gas
Used for Gas

Simethicone is an over-the-counter (OTC) anti-gas medication. It relieves pressure, bloating, and fullness from excess gas. There are many different dosage forms, like capsules, chewable tablets, and liquids. Both adults and children can take simethicone, but the age limits vary depending on each product. Side effects aren't common but can include nausea and diarrhea. Gas-X is a common brand-name of the medication. Many other brand-name and generic versions of simethicone are available.

Reviewed by:
reviewer
Sarah Lobello Pearson, PharmD
reviewer
Robert Chad Hakim, PharmD, BCCCP
Last reviewed on March 6, 2025
BasicsSide effectsPros & consPharmacist tipsFAQsDosageInteractionsCostAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Simethicone?

What is Simethicone used for?

  • Short-term relief of pressure, bloating, and fullness from excess gas

How Simethicone works

When there's too much gas in your intestines, it can cause uncomfortable or painful pressure, fullness, and bloating.

Simethicone is an anti-gas medication. It works by making the surface of gas bubbles more flexible. This allows gas bubbles to gather together and become larger bubbles in the intestines. Then, your body gets rid of the gas more easily.

When does Simethicone start working?
Time passed since treatment started:
MINUTES
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsGas-X, Little Remedies Gas Relief Drops, Infants' Mylicon
Drug ClassAntiflatulent
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityOver-the-counter

More on Simethicone essentials

Health: Simethicone: GettyImages-1286863005

Does Gas-X Really Help With Bloating?

Written by Sandy P. Bonfin, PharmD, BCPS
coupon-save-icon

Get your GoodRx coupon

Avg retail price
$6.75(save 61.14%)
GoodRx discount
$2.62
See prices
basics-icon

What are the side effects of Simethicone?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Side effects aren't common. See "Other Side Effects."

Other Side Effects

When do Simethicone possible side effects begin and end?
Time passed since treatment started:
MINUTES
HOURS
DAYS
WEEKS
MONTHS
Diarrhea
Nausea

Source: DailyMed

More on Simethicone side effects

Pharmacy: side effects gasx

What Are the Side Effects of Gas-X? Plus More FAQs About This Over-the-Counter Medication

Written by Nicole E. Cieri-Hutcherson, PharmD, BCPS, NCMP

The following side effects have also been reported

There have not been any common or important side effects reported with this medicine. However, if you notice any side effects, check with your doctor.

pros-and-cons

Pros and cons of Simethicone

thumbs-up

Pros

Available in many different forms (e.g., capsule, chewable tablet, liquid)

Available over the counter

Okay for infants to take

Few side effects

thumbs-down

Cons

Doesn't treat the cause of gas, just temporarily relieves the symptoms

Usually need to take several times a day

Only helps with gas, not other stomach problems like diarrhea or heartburn

Doesn't prevent you from getting gassy

pharmacist-tips

Pharmacist tips for Simethicone

pharmacist

  • Stop taking simethicone and contact your primary care provider if you have concerning symptoms, like vomiting, severe stomach pain, or bloody stool. These could be signs of a more serious problem that needs medical attention.

    • Check the labels on your medications to make sure you're not taking more than one product with simethicone. Some over-the-counter products for upset stomach also contain simethicone.

      More tips for children's simethicone 20 mg/0.3 mL liquid

      • Store the simethicone liquid at room temperature. Shake the bottle before you measure out the medication.

        • Use the oral syringe or dropper included in the package to measure out the correct dose of the simethicone liquid. Don't use any other syringes, droppers, spoons, or dosing cups to make sure you measure the right dose. Don't use household spoons because they're not accurate.

          • You can mix the simethicone drops with 1 ounce of cool water or infant formula. This can help make it easier for young children to take.

            • Place the simethicone drops into your child's mouth slowly. The tip of the oral syringe or dropper should be pointed towards your child's inner cheek. This helps prevent them from spitting out the medication. Clean the dropper after each use.

              faqs

              Frequently asked questions about Simethicone

              How long does simethicone take to work?
              Simethicone, commonly known as Gas-X, starts to relieve gas symptoms within a few minutes after you take it. If you've taken the medication and don't feel any relief, don't take another dose. Instead, contact your primary care provider about what to do.
              How often can you take simethicone?
              You can take simethicone after meals and at bedtime as needed for gas relief. But remember that there's a daily limit to how much you can take in a single day. This depends on each specific simethicone product. That's why it's important to check the label to see how much simethicone you can take each day. If you have gas that's not related to meals or need to take the medication more often, speak to your primary care provider. They can check for other medical conditions that might be going on.
              Is simethicone an antacid?
              No, simethicone isn't an antacid. Antacids help with acid reflux, whereas simethicone only relieves gas and bloating. If you have heartburn and gas, you might think about taking an antacid with simethicone. Some products combine both to help with gas, heartburn, and sour stomach at the same time. Examples include Mylanta (aluminum hydroxide / magnesium hydroxide / simethicone).
              Can you take Gas-X and Pepto Bismol?
              Yes, it's safe to take Pepto Bismol with Gas-X (a common brand name for simethicone). Both help with gas. But Pepto Bismol can also treat other symptoms of stomach upset, like diarrhea, nausea, indigestion, and burping. Talk to your primary care provider if your symptoms don't get better with these medications.
              Is it okay to take Gas-X when on Ozempic (semaglutide)?
              Yes. It's safe to take Gas-X (a common brand name for simethicone) while using Ozempic (semaglutide). Some people might find it helpful since gas and bloating can be side effects of Ozempic (semaglutide). Just remember that Gas-X won't prevent gas, it only helps relieve gas.
              Are dimethicone and simethicone the same?
              No. Dimethicone and simethicone are two completely different medications. Dimethicone is a topical product that you use on the skin to relieve dryness or irritation. Simethicone is an anti-gas medication that you take by mouth. It relieves pressure, bloating, and fullness from excess gas.
              Does Gas-X cause diarrhea?
              Gas-X, a common brand name for simethicone, can sometimes cause diarrhea as a side effect. But it's typically mild. And, it goes away when you stop the medication. If you have diarrhea, make sure to drink plenty of fluids to prevent dehydration. If the diarrhea continues, it might be best to stop taking the medication and talk to a healthcare professional about what to do.
              Can you take Gas-X while pregnant?
              Yes. Gas-X and other simethicone products are safe to take while pregnant. The medication doesn't get absorbed into the body. It's also safe to take while breastfeeding. Ask your obstetrician-gynecologist (OB-GYN) if you have more questions about gas relief while pregnant or nursing.
              GoodRxEducationalIcon

              How to save using GoodRx

              Compare Prices
              1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
              Select your free coupon
              2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
              Show coupon to your pharmacist
              3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
              Get free couponLearn more
              dosage

              Simethicone dosage forms

              The average cost for 30 chewable tablets of 80mg of Simethicone is $2.95 with a free GoodRx coupon. This is 56.29% off the average retail price of $6.75.
              capsule
              Capsule
              DosageQuantityPrice as low asPrice per unit
              125mg3 capsules$2.79$0.93
              180mg2 capsules$2.62$1.31
              chewable tablet
              Chewable tablet
              DosageQuantityPrice as low asPrice per unit
              80mg30 chewable tablets$2.95$0.10
              125mg30 chewable tablets$3.97$0.13
              dropper
              Dropper
              DosageQuantityPrice as low asPrice per unit
              15ml of 20mg/0.3ml2 droppers$7.16$3.58
              30ml of 20mg/0.3ml1 dropper$4.67$4.67

              Typical dosing for Simethicone

              Note: There are many brand-name and generic simethicone products. They can have different amounts of simethicone in them, so the dose might differ slightly. Be sure to check the medication box for the specific instructions for your product.

              Below are some examples:

              • Simethicone 125 mg chewable tablets (Gas-X Extra Strength)

                • Age 12 years and older: The typical dose is to chew 1 or 2 tablets as needed after meals and at bedtime. Chew or crush the tablets before swallowing. The maximum dose is 4 tablets within a 24-hour period.

              • Simethicone 250 mg capsules (Gas-X Maximum Strength)

                • Age 12 years and older: The typical dose is 1 or 2 capsules by mouth as needed after meals and at bedtime. Swallow the capsules with water. The maximum dose is 2 capsules within a 24-hour period.

              • Children's simethicone 20 mg/0.3 mL liquid (Little Remedies Gas Relief Drops, Infants' Mylicon)

                • Age under 2 years or weigh under 24 lbs: The typical dose is 0.3 mL by mouth as needed after meals and at bedtime. The maximum dose is 12 doses (3.6 mL total) within a 24-hour period.

                • Age 2 years and older or weigh at least 24 lbs: The typical dose is 0.6 mL by mouth as needed after meals and at bedtime. The maximum dose is 12 doses (7.2 mL total) within a 24-hour period.

              More on Simethicone dosage forms

              Health: Gas X: customer pharmacist 1401172653

              Gas-X Dosages: Your GoodRx Guide

              Written by Tegan Smedley, PharmD, APh
              interactions

              Interactions between Simethicone and other drugs

              Simethicone may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Simethicone. Please note that only the generic name of each medication is listed below.

              Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

              drug-cost

              How much does Simethicone cost?

              To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
              Gas-X (brand)
              GoodRx lowest price

              $2.62

              0
              Simethicone (generic)
              GoodRx lowest price

              $2.62

              (save 61.14%)
              View prices & coupons
              alternatives

              What are alternatives to Simethicone?

              There are a number of medications that your doctor can prescribe in place of Simethicone. Compare a few possible alternatives below.
              Simethicone
              Used for:

              • Short-term relief of pressure, bloating, and fullness from excess gas

              $2.62 Lowest GoodRx priceView Prices
              Bismuth subsalicylate (Pepto-Bismol)
              Used for:
              $7.26 Lowest GoodRx priceView Prices
              Mylanta Maximum Strength
              Used for:

              • Heartburn

              • Sour stomach

              • Indigestion

              • Gas (bloating, pressure, discomfort)

              $4.87 Lowest GoodRx priceView Prices
              images

              Simethicone images

              White Round G 103 - Simethicone 80mg Chewable Tablet (Mint)
              This medicine is White, Round Chewable Tablet Imprinted With "G 103".White Round G 103 - Simethicone 80mg Chewable Tablet (Mint)
              White Round G 103 - Simethicone 80mg Chewable Tablet (Mint)
              This medicine is White, Round Chewable Tablet Imprinted With "G 103".White Round G 103 - Simethicone 80mg Chewable Tablet (Mint)
              White Round 137 And 44 - Foster & Thrive Gas Relief Regular Strength 80mg Chewable Tablet (Mint)
              This medicine is White, Round Chewable Tablet Imprinted With "137" And "44".White Round 137 And 44 - Foster & Thrive Gas Relief Regular Strength 80mg Chewable Tablet (Mint)
              White Round 137 And 44 - Foster & Thrive Gas Relief Regular Strength 80mg Chewable Tablet (Mint)
              This medicine is White, Round Chewable Tablet Imprinted With "137" And "44".White Round 137 And 44 - Foster & Thrive Gas Relief Regular Strength 80mg Chewable Tablet (Mint)

              Get savings updates for Simethicone

              Receive price alerts, news, and other messages from GoodRx about Simethicone and other healthcare topics and relevant savings offers.

              By providing your email, you consent to receive marketing communications from GoodRx, which may include content and/or data related to men’s health, women's health, reproductive care, or sexual health. You agree to the GoodRx Terms of Use and acknowledge the Privacy Policy. You can unsubscribe at any time.

              References

              Best studies we found

              Centers for Disease Control and Prevention. (n.d.). PROTECT your child: Use the right tool to give the right dose.

              Haleon US Holdings LLC. (2024). Gas-X Extra Strength- simethicone tablet, chewable [package insert]. DailyMed.

              Haleon US Holdings LLC. (2024). Gas-X Maximum Strength Softgels- simethicone capsule, liquid filled [package insert]. DailyMed.

              View All References (2)

              Ingold, C. J., et al. (2023). Simethicone. StatPearls.

              Medtech Products Inc. (2025). Little Remedies Gas Relief Drops- simthicone liquid [package insert]. DailyMed.

              GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
              Was this page helpful?

              Browse medications

              View All

              Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.