Rituxan Dosage

Blood cancers

Your provider will determine your dose of Rituxan based on your body surface area (BSA) in m². This medication is typically given by a healthcare provider in a hospital or infusion clinic setting. Your provider might also give you other anticancer medications along with Rituxan.

• Non-Hodgkin’s lymphoma

  • Adults: The typical dose is 375 mg/m² given as an intravenous infusion. How often you’ll receive a dose usually ranges from weekly to every 8 weeks, depending on the type of NHL you have and where you are in the treatment process.
  • Children: Talk with your child’s provider.

• Chronic Lymphocytic Leukemia (CLL)

  • Adults: The typical dose is to receive one 375 mg/m² intravenous infusion before the start of chemotherapy. Then, your provider will raise your dose to 500 mg/m² infused on Day 1 of a 28-day chemotherapy cycle, for 2 to 6 cycles.

Autoimmune conditions

Your provider might also give you other medications along with Rituxan to treat your condition.

• RA

  • Adults: The typical starting dose is 1,000 mg infused IV for 2 doses, given 2 weeks apart. The typical maintenance dose is 1,000 mg infused once every 4 to 6 months, depending on your condition.

• GPA and MPA

  • Adults: Your provider will determine your dose of Rituxan based on your body surface area (BSA) in m². The typical starting dose is 375 mg/m² given as an intravenous infusion weekly for 4 weeks. The typical maintenance dose is 500 mg given as 2 doses 2 weeks apart, then 500 mg every 6 months.
  • Children: Ask your child’s provider.

• PV

  • Adults: The typical starting dose is 1,000 mg infused IV for 2 doses, given 2 weeks apart. The typical maintenance dose is 500 mg infused a year after the starting dose, then once every 6 months.