Rexulti

Older adults who also have dementia sometimes have some of the symptoms of schizophrenia, like hallucinations and delusions. This is called dementia-related psychosis, and it should not be treated with brexpiprazole (Rexulti). If brexpiprazole (Rexulti) is used for dementia-related psychosis, it can cause death. The cause of death is typically from heart problems, stroke, or infections. Let your provider know if you or your loved one has dementia before starting brexpiprazole (Rexulti).

Taking brexpiprazole (Rexulti) can put you at risk for suicidal thoughts and behavior. Your risk is higher if you're 24 years old or younger, or taking other antidepressants like sertraline (Zoloft) or fluoxetine (Prozac). Look out for worsening depression or any unusual changes in your mood, behavior, thoughts, or feelings, especially during the first few months of treatment or when your dose changes. Talk to your provider if you have any concerns about this side effect.

Brexpiprazole (Rexulti) can cause uncontrolled and possibly permanent muscle movements in the tongue, face, mouth, lips, neck, hands, arms, legs, and feet (tardive dyskinesia). To lower your risk of tardive dyskinesia, your provider will prescribe the lowest dose of brexpiprazole (Rexulti) for your symptoms. Get medical help right away if you notice any unusual movements you can't control. This side effect can sometimes occur even after you stop the medication.

Brexpiprazole (Rexulti) can cause neuroleptic malignant syndrome (NMS), which is a rare but serious condition that can lead to death. Be careful using brexpiprazole (Rexulti) if you're also on other medications that might cause NMS. Symptoms include a very high fever, stiff muscles, problems thinking clearly, a very fast or uneven heartbeat, and sweating. Stop taking brexpiprazole (Rexulti) and get medical attention right away if you experience these symptoms.

Brexpiprazole (Rexulti) can raise your blood sugar levels, sometimes to dangerous levels resulting in coma or death. Let your provider know if you have symptoms of high blood sugar, such as feeling very hungry or thirsty, urinating more often, stomach pain, weakness, or fruity-smelling breath.

Brexpiprazole (Rexulti) can make it difficult for you to think through your actions and control your behavior. It can lead to strong urges for and certain behaviors, such as gambling, eating, shopping, or sex. Because these behaviors can cause harm to yourself or others, your provider might lower your dose or stop the medication. If you or your loved ones notice a change in behavior, let your provider know.

Brexpiprazole (Rexulti) can lower the amount of white blood cells in your body and put you at higher risk for serious infection. You might need to get lab work done regularly to make sure your white blood cell count is healthy. If the levels are too low, your provider might stop your medication. Talk to your provider right away if you experience symptoms of an infection, including fever, weakness, or sore throat, while taking brexpiprazole (Rexulti).

Brexpiprazole (Rexulti) can cause sleepiness, dizziness, difficulties keeping your balance, and drops in blood pressure when you sit up or stand too quickly. This can result in fainting and falling. Sit up or stand up slowly, especially during the first few days after you start brexpiprazole (Rexulti) or when your provider raises your dose. Your risk of falls is higher if you have heart problems or if you don't have enough fluids in your body. Talk to your healthcare provider if you continue to experience dizziness while taking brexpiprazole (Rexulti).