Unoprostone is an eye drop that you give to yourself twice a day to lower pressure in the affected eye(s). The exact way that it works isn't fully known, but it's thought to help drain out the [liquid](https://www.aao.org/eye-health/anatomy/aqueous-humor) inside the front part of the eye. This helps lower eye pressure for people with high eye pressure or open-angle glaucoma.

Is unoprostone still available?

No, unoprostone has been [discontinued](https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=021214) and is no longer available in the United States. Unoprostone wasn't discontinued due to safety concerns, but rather for [business reasons](https://www.aao.org/headline/sucampo-discontinues-glaucoma-drug).

Are there currently available medications that are used in place of unoprostone?

Yes, there are several available [medications used to treat high eye pressure and glaucoma](https://www.goodrx.com/conditions/glaucoma/glaucoma-symptoms-causes-diagnosis-treatment) that are commonly used today. Examples of medications include [latanoprost (Xalatan)](https://www.goodrx.com/latanoprost/what-is) and [brimonidine (Alphagan P)](https://www.goodrx.com/brimonidine/what-is). Laser or surgical procedures can also lower pressure in the eye. Talk to your provider about which treatment is best for you.

Rescula

unoprostone

Used for Glaucoma

Unoprostone is an eye drop used to lower eye pressure in people with high eye pressure or open-angle glaucoma. It's no longer available in the United States, because it was discontinued.

Reviewed by:

Allison Gourley, PharmD

Kristianne Hannemann, PharmD

Last reviewed on July 5, 2022

What is Unoprostone?

What is Unoprostone used for?

High eye pressure
Open-angle glaucoma

Are you looking for information on lubiprostone (Amitiza) instead?

Drug facts

Common Brands	Rescula(brand no longer available)
Drug Class	Antiglaucoma
Controlled Substance Classification	Not a controlled medication
Generic Status	No lower-cost generic available
Availability	Discontinued

Common Brands

Rescula(brand no longer available)

Drug Class

Antiglaucoma

Controlled Substance Classification

Not a controlled medication

Generic Status

No lower-cost generic available

Availability

Discontinued

Common questions about Rescula

Rescula is an eye drop that you give to yourself twice a day to lower pressure in the affected eye(s). The exact way that it works isn't fully known, but it's thought to help drain out the liquid inside the front part of the eye. This helps lower eye pressure for people with high eye pressure or open-angle glaucoma.

No, Rescula has been discontinued and is no longer available in the United States. Rescula wasn't discontinued due to safety concerns, but rather for business reasons.

Yes, there are several available medications used to treat high eye pressure and glaucoma that are commonly used today. Examples of medications include latanoprost (Xalatan) and brimonidine (Alphagan P). Laser or surgical procedures can also lower pressure in the eye. Talk to your provider about which treatment is best for you.