The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Lower blood pressure (71%)
- Diarrhea (67%)
- Producing less urine (63%)
- Chills (52%)
- Vomiting (50%)
- Trouble catching your breath (43%)
- Rash (42%)
- Higher bilirubin levels (40%)
- Low blood cell count (up to 37%)
- Nausea (35%)
- Confusion (34%)
- Higher creatinine levels (33%)
- Fever (29%)
- Swelling in the arms, legs, feet (28%)
- Malaise (27%)
Less Common Side Effects
- Lung congestion or rattling sound
- Itching
- Weakness
- Mouth sores
- Sleepiness
- Lower appetite
- Weight gain
- Peeling skin
Proleukin serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Capillary leak syndrome: low blood pressure, swelling of body, arms, and legs, diarrhea, thickened blood
- Severe skin reaction: painful blisters, skin wounds, peeling skin, or red irritated eyes, sores in the mouth, nose, throat, or eyes
- Serious allergic reactions: trouble breathing, hives, tightness in the throat, dizziness, fast heartbeat, feeling confused, diarrhea, nausea, stomach pain
- Serious infections: fever, tiredness, chills, cough, trouble breathing
- Liver damage: dark urine, right-sided stomach pain, yellowing of the eyes or skin, tiredness, loss of appetite, nausea, vomiting
- Kidney problems: blood in the urine, painful urination, dark urine, not producing any urine
Source: DailyMed
The following Proleukin side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Agitation
confusion
dizziness
drowsiness
fever or chills
mental depression
shortness of breath
sores in the mouth and on lips
tingling of the hands or feet
unusual decrease in urination
unusual tiredness or weakness
weight gain of 5 to 10 pounds or more
Less common
blurred or double vision
faintness
fast or irregular heartbeat
loss of taste
rapid breathing
redness, swelling, and soreness of the tongue
trouble with speaking
yellow eyes and skin
Rare
Changes in menstrual periods
clumsiness
coldness
convulsions (seizures)
listlessness
muscle aches
pain or redness at injection site
sudden inability to move
swelling in the front of the neck
swelling of the feet or lower legs
weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
loss of appetite
skin rash or redness with burning or itching, followed by peeling
unusual feeling of discomfort or illness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
