The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Initial phase for active TB: The following side effects were reported by people who took [[EDITOR|DRUG_DISPLAY_NAME]] with other TB antibiotics.
- Low blood cell counts (up to 11%)
- Vomiting blood (8%)
- Coughing (6%)
- Sweating (5%)
- Elevated liver enzymes (5%)
Continuation phase for active TB: The following side effects were reported by people who took [[EDITOR|DRUG_DISPLAY_NAME]] with isoniazid.
Less Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Stomach upset or indigestion
- Headache
- Dizziness
- Rash
- Itching
Priftin serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Liver problems: severe nausea, vomiting, right-sided stomach pain, fatigue, low or no appetite, yellowing of the skin or eyes
- Low blood cell counts: fever, chills, weakness, unusual bruising or bleeding, blood in urine or stools
- Severe allergic reaction: rash; trouble breathing; swelling of the face, lips, tongue, or throat
- Severe skin reaction: rash, painful blisters, skin reddening, skin peeling, mouth sores, sore throat, fever, fatigue
- C. difficile-related diarrhea: rapid heart rate, fever, nausea, foul-smelling diarrhea, frequent bowel movements (even up to 15 times per day)
Source: DailyMed
The following Priftin side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Black, tarry stools
chills
coughing up blood
hoarseness
lower back or side pain
painful or difficult urination
pale skin
skin rash
trouble breathing with exertion
ulcers, sores, or white spots in the mouth
unusual bleeding or bruising
unusual tiredness or weakness
Less common
Bleeding gums
blood in the urine or stools
burning, dry, or itching eyes
excessive tearing of the eye
fast heartbeat
general feeling of illness
headache
irritation
joint pain, stiffness, or swelling
loss of appetite
pinpoint red spots on the skin
redness of the skin
swelling of the eyelids, face, lips, hands, or feet
swollen, painful, or tender lymph glands in the neck, armpit, or groin
tightness in the chest
trouble breathing or swallowing
Rare
blue or pale skin
burning feeling in the chest or stomach
burning, tingling, numbness, or pain in the hands, arms, feet, or legs
chest pain, possibly moving to the left arm, neck, or shoulder
cloudy or dark urine
cold sweat
collection of blood under the skin
confusion
deep, dark purple bruise
dizziness, fainting, or lightheadedness when getting up suddenly from a lying or sitting position
fast, pounding, or irregular heartbeat or pulse
indigestion
itching in the genital or other skin areas
lack or loss of strength
light-colored stools
noisy breathing
pain in the lower back or side
pain or burning in the throat
pains in the stomach, side, or abdomen, possibly radiating to the back
right upper stomach pain and fullness
scaling of the skin
seizures
stabbing pain
stomach upset
tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
thick, white vaginal discharge with mild or no odor
thickening of bronchial secretions
thirst
vaginal bleeding
voice changes
vomiting
yellow skin or eyes
Incidence not known
Blistering, peeling, or loosening of the skin
red skin lesions, often with a purple center
sensitivity of the skin to the sun
thinning of the skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Increased sweating
Less common
Belching
difficulty in moving
Rare
Discoloration of the skin
drowsiness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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