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Prasugrel

Prasugrel Side Effects

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on August 29, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • High blood pressure (8%)
  • High cholesterol (7%)
  • Headache (6%)
  • Bleeding of any kind (5%)
  • Back pain (5%)
  • Shortness of breath (5%)
  • Nausea (5%)
  • Dizziness (4%)
  • Cough (4%)
  • Low blood pressure (4%)
  • Fatigue (4%)

Less Common Side Effects

  • Chest pain
  • Pain in arms or legs
  • Diarrhea
  • Rash
  • Fever

Prasugrel serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe bleeding: feeling faint, lightheaded, dizziness, vomiting or coughing up blood, bloody or dark-colored stools, severe stomach pain or discomfort
  • Blood-clotting problem: headache; confusion; dizziness; tiredness; fever; small, purple spots on the skin; bruising; stomach pain; trouble breathing
When do Prasugrel possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Risk for minor bleeds (e.g., nosebleed)
Risk for major bleeds
Thrombotic thrombocytopenic purpura (TTP)
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Prasugrel side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Blurred vision

dizziness

headache

nervousness

pounding in the ears

slow or fast heartbeat

Less common

Black, tarry stools

bloating or swelling of the face, arms, hands, lower legs, or feet

chest pain or discomfort

chills

cough

difficult or labored breathing

fainting

fever

irregular heartbeat

lightheadedness, dizziness, or fainting

painful or difficult urination

rapid weight gain

sore throat

sores, ulcers, or white spots on the lips or in the mouth

swollen glands

tightness in the chest

tingling of the hands or feet

unusual bleeding or bruising

unusual tiredness or weakness

unusual weight gain or loss

Incidence not known

Change in mental status

dark or bloody urine

difficulty with speaking

fever

pale color of the skin

pinpoint red spots on the skin

seizures

weakness

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Back pain

diarrhea

nausea

pain in the arms or legs

rash

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.

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