Posluma
Posluma (flotufolastat F 18) is an radiopharmaceutical imaging agent that helps providers see areas of prostate cancer on a specific test known as a prostate-specific membrane antigen – positron emission tomography (PSMA-PET) scan. It’s for people with prostate cancer that might have come back after initial treatment (recurrent) or spread (metastasized) to other parts of the body. It’s given as an infusion through the vein before the PET scan. Side effects include diarrhea, injection site pain, and a rise in blood pressure.
What is Posluma (flotufolastat F 18)?
What is Posluma (flotufolastat F 18) used for?
- Diagnose suspected advanced prostate cancer, during a PSMA-PET scan
How Posluma (flotufolastat F 18) works
Posluma (flotufolastat F 18) is a radiopharmaceutical. It attaches to a particular protein found on the surface of certain cancer cells called prostate-specific membrane antigen (PSMA). Once attached, the radioactive portion of Posluma (flotufolastat F 18) lights up the areas with prostate cancer on a certain type of scan called a PSMA PET scan.
Drug facts
Common questions about Posluma (flotufolastat F 18)
Yes. The FDA approved Posluma (flotufolastat F 18) in May 2023.
No, Posluma (flotufolastat F 18) isn’t chemotherapy. Chemotherapy works by killing all fast-growing cells, including tumor cells. Posluma (flotufolastat F 18) doesn’t directly damage cancer cells. Instead, it lights up areas with prostate cancer so that your provider can see where the cancer is located. With that information, your provider can come up with a better treatment plan for you.
In studies, Posluma (flotufolastat F 18) didn’t have many side effects. In rare situations, some people reported diarrhea, a rise in blood pressure, and pain at the injection site. Talk with your provider if you’re concerned about side effects with this medication.
Not necessarily. With any test, there’s always a risk of detecting cancer when there isn’t any, or not detecting any cancer when there actually is cancer present. It’s likely that your treatment team will use the information from your scan together with blood tests and tissue samples to confirm your diagnosis and determine your treatment plan. If you are worried about a scan using the medication, discuss your concerns with your provider.
It’s a good idea to stay well-hydrated and urinate right before your PET scan with Posluma (flotufolastat F 18). After your scan, continue to stay hydrated and urinate frequently to reduce radiation exposure.
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Posluma (flotufolastat F 18) dosage
Typical dosage for Posluma (flotufolastat F 18)
