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Podofilox Coupon - Podofilox 3.5ml of 0.5% bottle of topical solution

podofilox

Generic Condylox
Used for HPV
Used for HPV

Podofilox (Condylox) is a topical antimitotic medication. It's available as podofilox 0.5% gel for treating genital and anal warts; it also comes as a podofilox 0.5% solution for treating genital warts only. The exact way podofilox (Condylox) works isn't well-understood, but it's thought to disrupt the growth of wart tissues. Podofilox (Condylox) is applied to the affected areas twice daily for 3 days, followed by a 4-day break. If needed, your healthcare team will ask you to repeat this treatment cycle up to 4 times. Some side effects of this medication include mild-to-moderate burning, pain, and swelling at the application site.

Reviewed by:
reviewer
Allison Gourley, PharmD
reviewer
Kristianne Hannemann, PharmD
Last reviewed on May 1, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesImagesReferencesPricesMedicare
basics-icon

What is Podofilox (Condylox)?

What is Podofilox (Condylox) used for?

How Podofilox (Condylox) works

Podofilox (Condylox) is a podophyllotoxin that comes from the roots of a plant species. It's a topical antimitotic skin product. The exact way podofilox (Condylox) works isn't well-understood, but it's thought to interfere with certain cell structures during cell division, which leads to death of wart tissue.

When does Podofilox (Condylox) start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsCondylox
Drug ClassTopical skin product
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$124.08(save 73.81%)
GoodRx discount
$32.50
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basics-icon

What are the side effects of Podofilox (Condylox)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Gel:
  • Burning (37%)
  • Inflammation (32%)
  • Itching (32%)
  • Sores (27%)
  • Pain (24%)
  • Bleeding (19%)
Solution:
  • Burning (64% in males, 78% in females)
  • Pain (50% in males, 72% in females)
  • Inflammation (71% in males, 63% in females)
  • Sores (67% in males and females)
  • Itching (50% in males, 65% in females)

Other Side Effects

  • Stinging
  • Redness
  • Peeling
  • Scabbing
  • Change in skin color
  • Tenderness
  • Dryness
  • Crusting
  • Cracked skin
  • Soreness
  • Ulcer
  • Swelling or edema (excess fluid under the skin)
  • Rash
  • Blisters
  • Tingling
  • Headache
When do Podofilox (Condylox) possible side effects begin and end?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Burning
Pain
Inflammation
Itching

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Bad odor (solution only)

bleeding of treated skin

blistering, crusting, or scabbing of treated skin

bloody urine (solution only)

burning feeling of treated skin

dizziness (solution only)

headache (gel only)

itching of treated skin

pain during sexual intercourse (solution only)

pain of treated skin

problems with foreskin of penis (solution only)

redness or swelling of treated skin

scarring of treated skin (solution only)

skin ulcers of treated skin

vomiting (solution only)

Symptoms of overdose

in order of occurrence

Nausea

vomiting

diarrhea

chills

fever

sore throat

unusual bleeding or bruising

oral ulcers

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Dryness of treated skin

peeling of treated skin

soreness or tenderness of treated skin

stinging or tingling of treated skin

trouble in sleeping (solution only)

Less common

Changes in color of treated skin (gel only)

skin rash (gel only)

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Podofilox (Condylox)

thumbs-up

Pros

Recommended topical medication used to treat genital and anal warts

A good option if you prefer treating your condition privately at home rather than getting in-office procedures

The solution and gel are available as generics

thumbs-down

Cons

Doesn't permanently get rid of the virus that causes warts, so warts can recur in the future

Not guaranteed to remove all of your warts

Applied twice daily

Skin reactions and irritation are common

pharmacist-tips

Pharmacist tips for Podofilox (Condylox)

pharmacist

  • It's important to use podofilox (Condylox) exactly as prescribed. When you first start using this medication, your prescriber might show you how to apply it correctly in order to get the best effect.

    • Before applying podofilox (Condylox), wash your hands with soap and water. Also remember to wash your hands after using this medication. If it gets in your eyes or anywhere that it doesn't belong, rinse well with water.

      • Apply podofilox (Condylox) using the provided applicator tip, or use a clean finger if you have the gel form. Try to put the medication only on the wart; it may help to use a small mirror to get it in the right place. Let the medication dry fully to avoid it from coming in contact with normal skin areas nearby.

        • Don't use more than 0.5 grams of gel or 0.5 mL of podofilox (Condylox) solution per day. If you aren't sure how much this is, ask your healthcare professional (HCP) or pharmacist.

          • Most side effects are mild or moderate and don't get worse with time. Severe reactions are less common and typically happen within the first 2 weeks of treatment. Let your HCP know if the side effects are causing serious problems for you, such as excessive pain, burning, or bleeding.

            • Don't use the medication for more than 3 days in a row. The recommended 1-week cycle is to apply it for 3 days, then stop for 4 days, then repeat as necessary. If podofilox (Condylox) doesn't rid your warts completely after 4 cycles, stop using the medication and talk to your prescriber. Don't use it for more than 4 cycles, since it's not guaranteed to work better and can even lead to more side effects.

              • Some viruses that cause warts can be passed to another person, even if you don't have visible signs of warts. If you've had anal or genital warts recently, it's best to avoid sex, or use barrier birth control (e.g., condoms, diaphragm) to prevent passing it to other people.

                faqs

                Frequently asked questions about Podofilox (Condylox)

                Can I buy podofilox (Condylox) over-the-counter?
                Podofilox (Condylox) requires a prescription from a healthcare professional (HCP). Getting an official diagnosis from your HCP is important, since anal and genital warts are typically transmitted through sexual contact. Your HCP might also need to test you for other sexually-transmitted infections (STIs).
                How long does podofilox (Condylox) take to work?
                You might need to use podofilox (Condylox) for one week or longer (maximum of 4 treatment cycles) before you start to notice improvements in the warts. Keep in mind that this medication might not completely get rid of your warts; in clinical studies of the gel form, only about a-quarter to a-third of people saw their warts clear after 4 cycles.
                How do I know if podofilox (Condylox) is working?
                Podofilox (Condylox) will cause your wart to start to die or become smaller. You might notice your wart changing from a fleshy skin color to a dry, crusted, dead look before it disappears altogether. You may need to repeat the podofilox (Condylox) treatment cycle until the wart is gone, but don't use it for more than 4 cycles.
                Does podofilox (Condylox) expire?
                Yes; podofilox (Condylox) expires, so don't keep using it beyond the date printed on the packaging. This is because it's not guaranteed to work well or be safe for you beyond the expiration date. If you need more medication, ask your HCP for a new prescription.
                Does podofilox (Condylox) work on skin tags?
                Podofilox (Condylox) is only approved for treatment of anal and genital warts. Don't use it for other conditions, including wart-like growths on other parts of the body. Speak with your dermatologist if you have a skin tag that you want to get rid of.
                What's the difference between imiquimod and podofilox (Condylox)?
                Both podofilox (Condylox) and imiquimod (Aldara, Zyclara) are prescription medications recommended to treat genital and anal warts. But they work in different ways. One of the main differences between them is how often they're applied. Imiquimod cream is typically applied at bedtime up to 2 to 4 months, depending on which strength of the medication you use. But podofilox (Condylox) is usually applied twice daily for 3 days in a row, followed by a 4-day break; this cycle can be repeated up to 4 times. Imiquimod can be used by people ages 12 years and older, while podofilox (Condylox) is for adults only. Talk with your healthcare professional regarding which wart treatment would be best for you.
                Does podofilox (Condylox) cause scarring?
                It's possible to get scarring from podofilox (Condylox), since this medication can damage the tissue on the surface of the wart. Let your prescriber know if you're concerned about scarring.
                Where should you use podofilox (Condylox)?
                Podofilox (Condylox) should only be used on anal and genital warts that are external (on the outside of the body). Don't use it to treat warts that are on mucous membranes, such as inside the urethra (the passage where urine comes out), vagina, or rectum (inside the anus). Don't use podofilox (Condylox) to treat warts on any other parts of the body or warts that cover a large area of skin.
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                warings-icon

                What are the risks and warnings for Podofilox (Condylox)?

                Podofilox (Condylox) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                risk-warning

                Use only for anal or genital warts

                Podofilox (Condylox) should only be used to treat anal or genital warts. You shouldn't use it on skin cancer, which can look like warts. Your healthcare professional (HCP) might get a biopsy of the area to make sure that this medication is appropriate to treat your condition.

                risk-warning

                Use only on skin

                Only use podofilox (Condylox) on the skin surface. Avoid getting it in your eyes. If this medication gets in your eyes, wash it out with lots of water and then get medical attention. Don't use podofilox (Condylox) on mucous membranes such as inside the urethra (the passage where urine comes out), vagina, or rectum (inside the anus).

                risk-warning

                Flammable (gel form only)

                The gel form of Podofilox (Condylox) can catch on fire easily, so keep it away from flames or lit cigarettes.

                dosage

                Podofilox (Condylox) dosage forms

                The average cost for 1 bottle of 3.5ml of 0.5% of Podofilox (Condylox) is $32.50 with a free GoodRx coupon. This is 73.81% off the average retail price of $124.08.
                bottle of topical solution
                Bottle of topical solution
                DosageQuantityPrice as low asPrice per unit
                3.5ml of 0.5%1 bottle$32.50$32.50
                tube of gel
                Tube of gel
                DosageQuantityPrice as low asPrice per unit
                3.5g of 0.5%1 tube$156.38$156.38

                Typical dosing for Podofilox (Condylox)

                • Adults: Apply to the affected area(s) in the morning and evening (every 12 hours) for 3 days, then stop for 4 days. If needed, your healthcare team will ask you to repeat this 1-week cycle (up to 4 times) until the wart is gone. If the wart isn't gone after 4 treatment cycles, ask your healthcare professionals (HCP) about other treatment options.

                Podofilox 0.5% solution is for genital warts only. Podofilox 0.5% gel is for both anal and genital warts.

                interactions

                Interactions between Podofilox (Condylox) and other drugs

                Podofilox (Condylox) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Podofilox (Condylox). Please note that only the generic name of each medication is listed below.

                Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

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                How much does Podofilox (Condylox) cost?

                To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
                Condylox (brand)
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                $32.50

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                Podofilox (Condylox) (generic)
                GoodRx lowest price

                $32.50

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                contraindications-icon

                Podofilox (Condylox) contraindications

                Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Podofilox (Condylox) will not be safe for you to take.

                • Skin cancer (which can look like warts)

                alternatives

                What are alternatives to Podofilox (Condylox)?

                There are a number of medications that your doctor can prescribe in place of Podofilox (Condylox). Compare a few possible alternatives below.
                Podofilox (Condylox)
                Used for:
                $32.50 Lowest GoodRx priceView Prices
                Imiquimod
                Used for:

                • Face or scalp actinic keratosis (scaly precancerous spot or growth on the skin) in adults - all brands and strengths

                • Genital and anal warts in adults and children 12 years and older - Zyclara 3.75% and Aldara 5% only

                • Superficial basal cell carcinoma (a type of skin cancer) in adults - Aldara 5% only

                $28.83 Lowest GoodRx priceView Prices
                images

                Podofilox (Condylox) images

                This medicine is Colorless Bottle Of Topical Solution.

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                References

                Best studies we found

                Allergan, Inc. (2024). Condylox- podofilox gel [package insert]. DailyMed.

                Centers for Disease Control and Prevention. (2021). Anogenital warts.

                DrugBank Online. (2024). Podofilox.

                View All References (5)

                Kodner, C. M., et al. (2004). Management of genital warts. American Family Physician.

                Padagis US LLC. (2023). Podofilox gel [package insert]. DailyMed.

                Padagis US LLC. (2023). Podofilox solution [package insert]. DailyMed.

                Shah, Z., et al. (2021). Podophyllotoxin: History, recent advances and future prospects. Biomolecules.

                Tyring, S., et al. (1998). Safety and efficacy of 0.5% podofilox gel in the treatment of anogenital warts. Archives of Dermatology.

                GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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