What should I watch for?
Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medicine for pain relief. Tolerance is normal and is expected if you take the medicine for a long time.
Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If you have pain, you have a medical reason to take pain medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
If you are also taking a narcotic medicine for pain or cough or another medicine that also causes drowsiness, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing or unusual sleepiness.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.
Your mouth may get dry. Chewing sugarless gum or sucking on hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Black, tarry stools
cough or hoarseness
difficult or troubled breathing
fever with or without chills
general feeling of tiredness or weakness
irregular, fast or slow, or shallow breathing
lower back or side pain
painful or difficult urination
pale or blue lips, fingernails, or skin
shakiness in the legs, arms, hands, or feet
shortness of breath
sores, ulcers, or white spots on the lips or in the mouth
trembling or shaking of the hands or feet
unusual bleeding or bruising
unusual tiredness or weakness
Incidence not known
Blistering, peeling, or loosening of the skin
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
decrease in the frequency of urination
difficulty in passing urine (dribbling)
difficulty with swallowing
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fast, slow, pounding, or irregular heartbeat or pulse
feeling of warmth
joint or muscle pain
loss of bladder control
loss of consciousness
pounding in the ears
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
red skin lesions, often with a purple center
red, irritated eyes
redness of the face, neck, arms, and occasionally, upper chest
swelling of the lower legs or arms
swelling of the face
tightness in the chest
total body jerking
upper abdominal or stomach pain
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Seeing, hearing, or feeling things that are not there
sleepiness or unusual drowsiness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Abdominal or stomach distress
hives or welts
redness of the skin
Incidence not known
Blistering, crusting, irritation, itching, or reddening of the skin
confusion about identity, place, and time
constricted, pinpoint, or small pupils (black part of the eye)
continuing ringing or buzzing or other unexplained noise in the ears
cracked, dry, or scaly skin
difficulty in focusing the eyes
false or unusual sense of well-being
loss of appetite
mood or mental changes
relaxed and calm feeling
trouble with sleeping
unable to sleep
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.