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PEMIGATINIB treats bile duct cancer. It may also be used to treat a type of bone marrow cancer (myeloid/lymphoid neoplasm). It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells. Compare kinase inhibitors.

Prescription Settings

What is Pemazyre?

What should I tell my doctor?

They need to know if you have any of these conditions:

High levels of phosphorous in the blood
Kidney disease
Liver disease
Vision problems
An unusual or allergic reaction to pemigatinib, other medications, foods, dyes, or preservatives
Pregnant or trying to get pregnant
Breast-feeding

How should I use this drug?

Take this medication by mouth. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the tablets whole. You can take it with or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop. There may be unused or extra doses in the bottle after you finish the dosing cycle. Talk to your care team if you have questions about your dose. Your care team may change your dose or tell you to stop taking this medication if you get side effects. Do not change your dose or stop taking it unless your care team tells you to.

Do not take this medication with grapefruit juice.

Talk to your care team about the use of this medication in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can unless it is more than 4 hours late. If it is more than 4 hours late, skip the missed dose. Take the next dose at the normal time.

Where should I store this drug?

Keep out of the reach of children and pets.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.