Oxaliplatin Side Effects
What should I watch for?
Your condition will be monitored carefully while you are receiving this medicine. You will need important blood work done while you are taking this medicine.
This medicine can make you more sensitive to cold. Do not drink cold drinks or use ice. Cover exposed skin before coming in contact with cold temperatures or cold objects. When out in cold weather wear warm clothing and cover your mouth and nose to warm the air that goes into your lungs. Tell your doctor if you get sensitive to the cold.
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
In some cases, you may be given additional medicines to help with side effects. Follow all directions for their use.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.
Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
Call your doctor or health care professional if you get diarrhea. Do not treat yourself.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Abnormal tongue sensation
black, tarry stools
blistering, peeling, redness, or swelling of the palms of the hands or bottoms of the feet
blood in the urine or stools
burning, prickling, itching, or tingling of the skin
decreased feeling, or pain in the hands, feet, around the mouth, or throat
difficulty performing daily activities such as writing, buttoning, swallowing, or walking
difficulty with articulating words
difficulty with breathing
difficulty with moving
difficulty with swallowing
increase in heart rate
muscle pain or stiffness
numbness, pain, tingling, or unusual sensations in the palms of the hands or bottoms of the feet
pain in the chest, groin, or legs, especially the calves
pain in the joints
painful or difficult urination
pinpoint red spots on the skin
sensation of pins and needles
sores, ulcers, or white spots on the lips or in the mouth
swelling or inflammation of the mouth
troubled breathing with exertion
unusual tiredness or weakness
loss of appetite
nausea or vomiting
numbness or tingling in the hands, feet, or lips
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
tightness in the chest
Incidence not known
Back, leg, or stomach pains
blue-yellow color blindness
changes in patterns and rhythms of speech
electric shock-like sensation that moves down the back and into the legs following a bending movement of the neck
general body swelling
irregular heartbeat, recurrent
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
loss of deep tendon reflexes
muscle cramps or spasms
pain and fullness in the right upper abdomen
severe stomach cramps or tenderness
trouble with speaking
twitches of the muscle visible under the skin
weakness of the muscles in your face
yellow eyes or skin
Get emergency help immediately if any of the following symptoms of overdose occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Acid or sour stomach
body aches or pain
feeling unusually cold, shivering
loss of voice
stomach discomfort, upset, or pain
Bad, unusual, or unpleasant (after) taste
bloated or full feeling
burning while urinating
change in taste
dryness or soreness of the throat
excess air or gas in stomach or intestines
feeling of warmth
rapid weight gain
redness of the face, neck, arms, and occasionally upper chest
tender, swollen glands in the neck
thinning of the hair
unusual tearing of the eyes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.