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Cisplatin

Cisplatin Side Effects

Jenny Zhang, PharmD, BCOPCydnee Ng, PharmD
Reviewed by Jenny Zhang, PharmD, BCOP, Cydnee Ng, PharmD
Last reviewed on July 11, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea
  • Vomiting
  • Changes in hearing
  • Abnormal blood cell counts
  • Numbness or tingling in the hands or feet

Cisplatin serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Infections: repeated fevers, chills, cough, trouble breathing, severe diarrhea, vomiting, painful or frequent urination
  • Serious bleeds: bleeding or bruising that doesn’t stop or go away, large amount of bleeding, blood in the urine, throwing up blood, bloody or black and tarry stool
  • Kidney problems: blood in the urine (pink or red urine), dark urine, painful urination, difficulty urinating

Source: DailyMed

The following Cisplatin side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Black, tarry stools

blood in urine or stools

burning, numbness, tingling, or painful sensations

change in frequency of urination or amount of urine

cough or hoarseness

difficulty in breathing

dizziness

drowsiness

feeling of fullness in the ears

fever or chills

increased thirst

loss of appetite

loss of balance

loss of hearing

lower back or side pain

nausea or vomiting

painful or difficult urination

pinpoint red spots on skin

ringing or buzzing in the ears

swelling of the feet or lower legs

trouble in hearing

unsteadiness or awkwardness

unusual bleeding or bruising

weakness in the arms, hands, legs, or feet

Incidence not known

Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

bleeding gums

blindness

blue-yellow color blindness

blurred vision

chest pain or discomfort

decreased vision

eye pain

fast heartbeat

general body swelling

headache

leg pain

nosebleeds

pain or discomfort in the arms, jaw, back or neck

pains in the stomach, side, or abdomen, possibly radiating to the back

pale skin

sweating

unusual tiredness or weakness

weight loss

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Bloating

constipation

diarrhea

hair loss or thinning

indigestion

loss of appetite

muscle cramps

rash

swelling or inflammation of the mouth

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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