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Otiprio

ciprofloxacin
Used for Ear Infection
Used for Ear Infection

Otiprio (ciprofloxacin) is an antibiotic that's given directly in the ear to treat certain ear infections in people age 6 months and older. This medication belongs to the fluoroquinolone drug class. It's given as a single dose into the infected ear by a healthcare professional. Side effects include feeling irritated and having common cold symptoms like runny nose. Otiprio (ciprofloxacin) is no longer available in the United States because it was discontinued. There's a different brand of ciprofloxacin ear drops that's still available called Cetraxal.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Cydnee Ng, PharmD
Last reviewed on February 4, 2024
BasicsFAQsAlternativesReferencesPricesMedicare
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What is Otiprio (ciprofloxacin)?

What is Otiprio (ciprofloxacin) used for?

How Otiprio (ciprofloxacin) works

Otiprio (ciprofloxacin) is a fluoroquinolone (or "quinolone") antibiotic. It blocks certain enzymes (proteins) that bacteria need to grow, repair their genetic material (DNA), and survive. By blocking this process, Otiprio (ciprofloxacin) kills bacteria.

Are you looking for information on ciprofloxacin ear drops (Cetraxal) or ciprofloxacin eye drops and ointment (Ciloxan) instead?

Drug Facts

Common BrandsOtiprio
Drug ClassFluoroquinolone antibiotic
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
faqs

Frequently asked questions about Otiprio (ciprofloxacin)

Is Otiprio (ciprofloxacin) still available?
No, Otiprio (ciprofloxacin) is no longer available in the United States because it was discontinued. It's not clear why the manufacturer discontinued the medication.
Is Otiprio (ciprofloxacin) a sulfa drug?
No. Ciprofloxacin isn't a sulfa drug, so it's safe to take Otiprio (ciprofloxacin) if you have a sulfa allergy.
Is Otiprio (ciprofloxacin) a penicillin?
No, ciprofloxacin isn't a penicillin. It's a type of antibiotic called a fluoroquinolone (or "quinolone").
Can you take Otiprio (ciprofloxacin) if you're allergic to penicillin?
Yes, you can safely take Otiprio (ciprofloxacin) even if you're allergic to penicillin. Ciprofloxacin is a fluoroquinolone antibiotic, whereas penicillin is a beta-lactam antibiotic. These antibiotics work differently in your body to fight bacterial infections. If you're allergic to either penicillin or ciprofloxacin, it doesn't mean you'll be allergic to the other.
Does Otiprio (ciprofloxacin) cover Pseudomonas?
Yes, ciprofloxacin covers (or fights against) the Pseudomonas bacteria. The most common type of Pseudomonas that causes infections is called Pseudomonas aeruginosa. Otiprio (ciprofloxacin) can be used for an ear infection that's caused by Pseudomonas aeruginosa.
How is Otiprio (ciprofloxacin) given?
Otiprio (ciprofloxacin) is given by a healthcare professional at a medical office. The medication is injected directly into the ear. It can also be given as drops into the ear.
What are common side effects of Otiprio (ciprofloxacin)?
The most common side effects of Otiprio (ciprofloxacin) are common cold symptoms, feeling irritable, and runny nose. Other side effects can include headache, itchiness in the ear, and ear discomfort.
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alternatives

What are alternatives to Otiprio (ciprofloxacin)?

There are a number of medications that your doctor can prescribe in place of Otiprio (ciprofloxacin). Compare a few possible alternatives below.
Otiprio (ciprofloxacin)
Used for:
View Prices
Ciprofloxacin (Cetraxal)
Used for:

  • Outer ear infection

$25.23 Lowest GoodRx priceView Prices
Ofloxacin ear drops
Used for:
$14.00 Lowest GoodRx priceView Prices

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References

Best studies we found

Bush, L. M., et al. (2024). Pseudomonas infections. Merck Manual Consumer Version.

Centers for Disease Control and Prevention. (2024). About Pseudomonas aeruginosa.

Drugs@FDA: FDA-Approved Drugs. (n.d.). Otiprio. U.S. Food and Drug Administration.

View All References (2)

Otonomy, Inc. (2018). Otiprio® (ciprofloxacin otic suspension), for intratympanic or otic use [package insert]. U.S. Food and Drug Administration.

Pandey, N., et al. (2023). Beta-lactam antibiotics. StatPearls.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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