The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Nasal discomfort (29%)
- Headache (27%)
- Nausea (17%)
- Dizziness (9%)
- Hot flush (8%)
- Vomiting (6%)
- Anxiety (5%)
Less Common Side Effects
- Feeling tired
- Stuffy nose
- Throat irritation
- Nose pain
Opvee serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Sudden opioid withdrawal symptoms: feeling anxious or irritable, pain, fast heartbeat, sweating, vomiting, shakiness
Source: Prescribing Information
The following Opvee side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Chills
- Dizziness
- Headache
- Irritability
- Irritation inside the nose or throat
- Nausea
- Vomiting


