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Nulojix Side Effects

What should I watch for?

Your condition will be monitored carefully while you are receiving this medicine.

In some patients, this medicine may cause a serious brain infection that may cause death. If you have any problems seeing, thinking, speaking, walking, or standing, tell your doctor right away. If you cannot reach your doctor, urgently seek other source of medical care.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever. Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Abdominal or stomach pain


black, tarry stools

bladder pain

bloating or swelling of the face, arms, hands, lower legs, or feet

bloody or cloudy urine

blurred vision

bone pain

burning while urinating

chest pain





cough or hoarseness

decreased frequency or amount of urine

decreased urine output


difficult or labored breathing

difficult, burning, or painful urination


dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


dry mouth


fast or irregular heartbeat


frequent urge to urinate



inability to move the arms and legs

increased blood pressure

increased thirst


itching in other skin areas


loss of appetite

loss of bladder control

lower back or side pain

mood or mental changes

muscle pain or cramps

muscle spasms (tetany) or twitching

nausea or vomiting


numbness or tingling in the hands, feet, or lips

pale skin

pounding in the ears

rapid weight gain


shortness of breath

slow or fast heartbeat

sore throat

sores, ulcers, or white spots on the lips or in the mouth


sudden decrease in the amount of urine

sudden numbness and weakness in the arms and legs


swelling of the face, ankles, or hands

swollen glands

tightness in the chest


troubled breathing

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

unusual weight gain or loss

weakness or heaviness of the legs

weight gain


Less common

Back pain

coughing or spitting up blood


joint pain, stiffness, or swelling

loss of appetite

night sweats

persistent non-healing sore

pink growth reddish patch or irritated area

shiny bump

sudden high fever or low-grade fever for months

swelling of the feet or lower legs

weight gain

white, yellow, or waxy scar-like area

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Abdominal or stomach cramps

blemishes on the skin

body aches or pain

collection of blood under the skin

cough producing mucus

deep, dark purple bruise


difficulty having a bowel movement (stool)

difficulty with moving

dry mouth

ear congestion

flushed, dry skin

fruit-like breath odor

hair loss or thinning of the hair

increased hunger

increased sweating

increased urination

itching, pain, redness, or swelling

loss of consciousness

loss of voice

muscle cramps in the hands, arms, feet, legs, or face

muscle or bone pain

muscle pain or stiffness

numbness and tingling around the mouth, fingertips, or feet

pain in the joints


shakiness in the legs, arms, hands, or feet

shortness of breath



swelling or inflammation of the mouth

tightness in the chest


trouble sleeping

unable to sleep

unexplained weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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