Typical dosage for Nexterone
Amiodarone (Nexterone) comes as concentrate solution in vials and a pre-mixed injection (brand name Nexterone).
- Loading dose: The typical loading dose is about 1,000 mg infused over the first 24 hours. Usually, the cardiology team will give 150 mg as a rapid infusion over the first 10 minutes, then give 360 mg more slowly over the next 6 hours. After that, they'll give the rest of the loading dose (540 mg) even more slowly, over the remaining 18 hours.
- Maintenance dose: After the first 24 hours, the typical maintenance dose is 720 mg infused slowly every 24 hours, usually for 2 to 3 weeks. The cardiology team will typically give an additional 150 mg over 10 minutes to stabilize any breakthrough arrhythmias.
Once the heart rhythm stabilizes and you're able to take medication by mouth, the team will transition you to amiodarone oral tablets (Pacerone).
