Mulpleta (lusutrombopag) is used to raise the platelet count in adults with long-term liver problems scheduled to undergo a procedure. Although it's convenient because it's taken by mouth once per day for a total of 7 days, it's expensive since it's a brand medication only.
Treatment of low platelets in adults with long-term liver disease scheduled to undergo a procedure
Mulpleta (lusutrombopag) is a thrombopoietin receptor agonist, meaning it acts like TPO. TPO is a natural hormone that tells your bone marrow to make more platelets. So Mulpleta (lusutrombopag) works by raising your platelets and helps to lower your risk for bleeding in preparation for a procedure.
Source: DailyMed
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
Taken once a day by mouth
Only need to take for 7 days before the procedure
Generally well tolerated with few side effects
Only used in people with long-term liver problems undergoing a procedure
Available as a brand name only, so it can be expensive
Can't be used in children
Take Mulpleta (lusutrombopag) with or without food. If it hurts your stomach when you take it, try taking it with food to help.
Try to take Mulpleta (lusutrombopag) at the same time each day. If you miss a dose, take it as soon as you remember on the same day, then return to your normal schedule the next day.
You'll need to get your platelet count measured before starting Mulpleta (lusutrombopag) and at least 2 days before your procedure. Make sure to mark your calendar with your appointments to see your provider and get your blood drawn to avoid potentially delaying your procedure. Depending on what your platelet count is, you might need to postpone your procedure if your platelet count is too low.
It's not recommended to breastfeed when you're taking Mulpleta (lusutrombopag). Wait at least 28 days after your last dose of Mulpleta (lusutrombopag) before breastfeeding due to the potential of side effects in your baby.
Mulpleta (lusutrombopag) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: History of conditions that raise your risk for blood clots
Since Mulpleta (lusutrombopag) raises the number of platelets in your blood, there is a risk of clotting, including a condition called portal vein thrombosis. Portal vein thrombosis is a clot in the major vein of your liver. This is rare though, as it happened in about 1% of people taking Mulpleta (lusutrombopag) during clinical studies. Still, contact your provider as soon as possible if you experience stomach pain, nausea, or fever because these might be signs of portal vein thrombosis.
Dosage | Quantity | Price as low as | Price per unit |
---|---|---|---|
7 tablets of 3mg | 1 dose pack | $8375.98 | $8375.98 |
The typical dose is 3 mg by mouth once a day for 7 days.
Treatment of low platelets in adults with long-term liver disease scheduled to undergo a procedure
Low platelet levels in adults with chronic liver disease (CLD) before a scheduled procedure
Low platelet levels in adults with chronic immune thrombocytopenia (ITP) when other medications haven’t worked
By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx.
Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.