provider image
Welcome! You’re in GoodRx for healthcare professionals. Now, you’ll enjoy a streamlined experience created specifically for healthcare professionals.
Skip to main content

Mirena

levonorgestrel
Used for Birth Control
Used for Birth Control

Mirena (levonorgestrel) is a progestin intrauterine device (IUD). It's approved for females of reproductive age to prevent pregnancy for up to 8 years. It can also help relieve heavy menstrual periods for up to 5 years. Mirena IUD (levonorgestrel) is inserted into the uterus by a provider in their office. Some of the more common side effects of Mirena IUD (levonorgestrel) include changes to menstrual bleeding and pelvic pain. Rarely, it can also cause some weight gain.

Last reviewed on November 30, 2023
basics-icon

What is Mirena IUD (levonorgestrel)?

What is Mirena IUD (levonorgestrel) used for?

How Mirena IUD (levonorgestrel) works

Mirena IUD (levonorgestrel) is a small device placed in the uterus that slowly releases a progestin hormone called levonorgestrel. This hormone prevents pregnancy by stopping your ovaries from releasing an egg. Levonorgestrel also makes it difficult for sperm to enter the uterus and for a fertilized egg to implant in the uterus. Mirena IUD (levonorgestrel) works to treat heavy periods by thinning the lining of your uterus.

Are you looking for information on levonorgestrel (Plan B One-Step) oral tablet instead?

Drug Facts

Common BrandsMirena
Drug ClassProgestin
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only

More on Mirena IUD (levonorgestrel) essentials

basics-icon

What are the side effects of Mirena IUD (levonorgestrel)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Abnormal uterine bleeding (up to 32%)
  • Stomach or pelvic pain (23%)
  • No menstrual bleeding (18%)
  • Headaches or migraines (16%)
  • More vaginal discharge than usual (15%)
  • Vaginal irritation (11%)

Other Side Effects

  • Breast pain
  • Ovarian cyst
  • Menstrual cramps
  • Back pain
  • Acne
  • Depression
  • Hair loss
  • Facial hair growth
  • Expulsion (the device comes out on its own)
  • Weight gain
  • Nausea

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Ectopic pregnancy: severe, unexplainable pelvic pain along with unusual vaginal bleeding
  • Severe infection: fever, chills, confusion, fatigue

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Absent, missed, or irregular menstrual periods

longer or heavier menstrual periods

mild bloating

stomach or pelvic pain

stopping of menstrual bleeding

unusually heavy or unexpected menstrual bleeding

uterine bleeding between menstrual periods

vaginal bleeding or spotting

Less common

Blurred vision

cramps

dizziness

headache

heavy bleeding

itching of the vagina or genital area

nervousness

pain

pain during sexual intercourse

pale skin

pounding in the ears

slow or fast heartbeat

swelling

thick, white vaginal discharge with mild or no odor

trouble breathing

unusual bleeding or bruising

unusual tiredness or weakness

white or brownish vaginal discharge

Rare

Chills

confusion

dizziness, lightheadedness, fainting

fast heartbeat

fast, weak pulse

fever

pale, cold, clammy skin

rapid, shallow breathing

sudden increase in stomach or shoulder pain

sweating

unusual or large amount of vaginal bleeding

Incidence not known

Clear or bloody discharge from the nipple

dimpling of the breast skin

dull or aching stomach pain

foul-smelling vaginal discharge

increased blood pressure

increased urge to urinate

inverted nipple

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

lump in the breast or under the arm

pain during urination

persistent crusting or scaling of the nipple

redness or swelling of the breast

severe stomach pain or cramping

sharp pain on insertion

shivering fever

sores on the skin of the breast that does not heal

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Blemishes on the skin

depression

pimples

Less common

Back pain

breast tenderness or pain

decreased interest in sexual intercourse

full or bloated feeling

hair loss

hives or welts, itching, or rash

increased hair growth, especially on the face

increased weight

loss in sexual ability, desire, drive, or performance

nausea

pressure in the stomach

redness of the skin

skin rash, encrusted, scaly, and oozing

swelling of the stomach area

thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Mirena IUD (levonorgestrel)

thumbs-up

Pros

Work better than (works better) oral birth control pills to prevent pregnancy

Can be used while breastfeeding

Can be inserted in your provider's office within a few minutes and without any kind of sedation (medication to put you asleep)

Helps relieve heavy menstrual periods for up to 5 years

thumbs-down

Cons

Can raise your risk of an ectopic pregnancy

Breakthrough bleeding and irregular cycles are common side effects

Not safe to use if you have liver problems or have ever had breast, uterine, or cervical cancer

Can't be used if you have uterine fibroids, are prone to pelvic infections, or have pelvic inflammatory disease (PID)

pharmacist-tips

Pharmacist tips for Mirena IUD (levonorgestrel)

pharmacist
  • After the Mirena IUD (levonorgestrel) has been placed, there will be 2 thin threads hanging inside the vagina. Your provider might recommend that you check for these threads once a month with a clean finger. Never tug or pull on the threads when you're checking for them. If you can't feel them, call your provider right away because it might be a sign that Mirena IUD (levonorgestrel) isn't positioned properly.

    • The Mirena IUD (levonorgestrel) can affect your menstrual cycle and menstrual bleeding. It's possible you might even have no period while using this device. Call your provider if this is concerning to you or if your bleeding becomes very heavy.

      • The Mirena IUD (levonorgestrel) can be used while breastfeeding. The medication from the device won't hurt your baby, but you might notice a slight drop in your milk supply. Follow up with your provider about the best time to get the IUD inserted.

        • It's possible for your body to push the Mirena IUD (levonorgestrel) back out of your uterus into your vagina. If this happens, call your healthcare provider right away and use a back-up method of protection (e.g., condoms, diaphragms) until you have a new device placed.

          More on Mirena IUD (levonorgestrel) tips

          faqs

          Frequently asked questions about Mirena IUD (levonorgestrel)

          How long does Mirena IUD (levonorgestrel) last?
          Mirena IUD (levonorgestrel) works to prevent pregnancy for up to 8 years. If you're using Mirena IUD (levonorgestrel) to relieve heavy menstrual bleeding, you can use it for up to 5 years. If you no longer want to use it, your provider can help you remove the IUD at any time.
          Does Mirena IUD (levonorgestrel) stop periods?
          Mirena IUD (levonorgestrel) can stop your menstrual periods, though it typically happens later on during treatment. When you first start Mirena IUD (levonorgestrel), you're more likely to experience spotting or breakthrough bleeding, especially within the first 3 to 6 months. Studies show that about 20% of people using Mirena IUD (levonorgestrel) noticed their periods going away altogether (amenorrhea) within a year of treatment. Talk with your provider if you've more questions about how Mirena IUD (levonorgestrel) might affect your periods.
          Does Mirena IUD (levonorgestrel) cause weight gain?
          While not common, some people reported weight gain while using Mirena IUD (levonorgestrel). Research suggests that the progestin hormone causes your body to hold onto more water, which might make you feel bloated. If you notice that you've gained a lot of weight since starting on the Mirena IUD (levonorgestrel), let your provider know.
          How soon after Mirena IUD (levonorgestrel) is placed is it effective?
          If your provider inserts Mirena IUD (levonorgestrel) while you're having your period, it'll start working right away to prevent pregnancy. But if Mirena IUD (levonorgestrel) is inserted when you're not on your period, you'll need to use a back-up birth control method, like condoms, for the first 7 days.
          When can you have sex after Mirena IUD (levonorgestrel)?
          As long as your provider didn't give you specific restrictions, you can technically have sex after Mirena IUD (levonorgestrel) is in place. But, you might consider waiting a few days after the insertion before you have sex. Some people feel cramping or discomfort for the first few days (and sometimes longer) after Mirena IUD (levonorgestrel) is put in place. Keep in mind that if your provider inserted Mirena IUD (levonorgestrel) when you're not on your period, you'll need to use a condom if you have sex within the first 7 days of insertion.
          What to expect after Mirena IUD (levonorgestrel) insertion?
          You might experience some cramping after your provider inserts Mirena IUD (levonorgestrel), but this is normal. If your provider says it's okay, try to take some over-the-counter pain medication, like (acetaminophen) Tylenol or ibuprofen (Advil), an hour before your appointment and also afterwards. You can also anticipate having some irregular bleeding after Mirena IUD (levonorgestrel) insertion; this can last for a few months. Generally, side effects after Mirena IUD (levonorgestrel) insertion should get better over time.
          Is Mirena IUD (levonorgestrel) a copper IUD?
          No. Mirena IUD (levonorgestrel) is a hormonal IUD that releases a lab-made form of progesterone call progestin. If you'd prefer a hormone-free IUD, ask your provider about the copper IUD, Paragard, instead. Check out this article to learn about the differences between the two types of IUDs.
          Can my male partner feel the Mirena IUD (levonorgestrel) IUD during sex?
          Since Mirena IUD (levonorgestrel) is placed in your uterus and not your vagina, your partner shouldn't feel it during sex. Mirena IUD (levonorgestrel) has a string that hangs down an inch or two into the vagina, your partner might be able to feel that. If this is bothersome, talk with your provider. Rarely, your partner might feel the actual IUD - this is likely a sign that the IUD isn't placed correctly or has moved out of place. Let your provider know right away if this happens.
          GoodRxEducationalIcon

          How to save using GoodRx

          Compare Prices
          1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
          Select your free coupon
          2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
          Show coupon to your pharmacist
          3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
          Get free couponLearn more
          warings-icon

          What are the risks and warnings for Mirena IUD (levonorgestrel)?

          Mirena IUD (levonorgestrel) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

          risk-warning

          Ectopic pregnancy

          • Risk factors: Previous ectopic pregnancy | Past surgery performed on your fallopian tubes | Current pelvic infection

            Ectopic pregnancies happen when a fertilized egg implants somewhere other than your uterus. They're very rare, but can be life-threatening and sometimes need to be treated with surgery. Progestin-only contraception, including the Mirena IUD (levonorgestrel) IUD, can raise your risk of ectopic pregnancies. Pregnancy is rare with all IUDs, but if you do become pregnant while the Mirena IUD (levonorgestrel) IUD is inserted, the chance of it being an ectopic pregnancy is high. If you experience unexplained or severe pelvic pain along with unusual vaginal bleeding, let your provider know.

            If you do become pregnant after the Mirena IUD (levonorgestrel) IUD was placed, contact your provider right away. Your provider will recommend for you to remove Mirena IUD (levonorgestrel) because keeping it in place raises your risk for complications such as miscarriage and infection.

            risk-warning

            Sepsis (blood infection)

            • Risk factors: Placement of device in an unhygienic environment

              Sepsis is when bacteria infect your bloodstream, and it can be life-threatening. Your risk of getting this infection goes up if Mirena IUD (levonorgestrel) wasn't placed using proper antibacterial technique. Sepsis would typically happen shortly after the device was inserted, sometimes even within a few hours. Tell your provider right away if you have pelvic pain, a high fever, or any other symptoms of being sick shortly after the device was placed.

              risk-warning

              Pelvic inflammatory disease (PID)

              • Risk factors: History of or current pelvic inflammatory disease | Current sexually transmitted infections | Multiple sex partners

                IUDs raise your risk of developing pelvic inflammatory disease (PID) because there's always a small chance bacteria can get into your uterus when the device is placed. Because of this, the Mirena IUD (levonorgestrel) IUD isn't safe to use if you've ever had or are prone to PID. If you start to experience any unusual pelvic pain, funny-smelling discharge, unusual vaginal bleeding, sores or cuts in your genital area, or a high fever, call your provider right away.

                risk-warning

                Uterine injury

                • Risk factors: Placing the Mirena IUD (levonorgestrel) IUD less than 6 weeks after giving birth

                  There's a very small chance that the Mirena IUD (levonorgestrel) IUD can uterine injury (perforation), which is extremely dangerous. It also prevents the Mirena IUD (levonorgestrel) IUD from working properly, meaning you can get pregnant if this happens. The risk of perforation is higher if you've the Mirena IUD (levonorgestrel) IUD placed less than 6 weeks after you give birth to a baby. Your provider will need to remove the IUD if there's an injury, and this might require surgery. Tell your provider right away if you can't feel the threads that hang freely inside your vagina after it has been placed.

                  risk-warning

                  Body ejecting the device

                  • Risk factors: Placing the Mirena IUD (levonorgestrel) IUD less than 6 weeks after giving birth

                    There is a small chance the body can eject the Mirena IUD (levonorgestrel) IUD from the uterus back into your vagina. If this happens, the device won't be working and you can get pregnant. Your risk of having this happen is higher if you have the IUD placed less than 6 weeks after you gave birth. If you notice your menstrual bleeding suddenly becomes heavier than usual, this could be a sign your body is ejecting the Mirena IUD (levonorgestrel) IUD. Tell your provider if this happens and use non-hormonal protection (e.g., condoms, diaphragms) until your provider places a new device or tells you the device is in the right place.

                    risk-warning

                    Irregular periods

                    The Mirena IUD (levonorgestrel) IUD can cause you to experience irregular menstrual periods. Most people will have heavier or longer periods for the first 3 to 6 months after the device is placed, followed by very light or no periods. But, you might notice changes of any kind to your menstrual cycle while using the Mirena IUD (levonorgestrel) IUD. If you're worried about the changes to your periods, talk to your provider, especially if you're having sudden or unusually heavy bleeding after the first 3 to 6 months. This could be a sign that the device is not in the correct place. If you don't get your period within 6 weeks of your last one, take a pregnancy test to make sure you aren't pregnant.

                    risk-warning

                    Ovarian cysts

                    Since Mirena IUD (levonorgestrel) is located within the uterus, it can sometimes lead to the development of ovarian cysts. Although most ovarian cysts don't cause any symptoms, some might cause pelvic pain or pain during sex. In most cases, the cysts go away on their own after a few months, but your provider will keep an eye on things just to make sure. Surgery is usually not required for these.

                    risk-warning

                    Possible risk of cancer

                    People who have or have had breast cancer shouldn't use hormonal birth control, including Mirena IUD (levonorgestrel). Certain types of breast cancer can be sensitive to hormones, and might grow in the presence of hormones.

                    dosage

                    Mirena IUD (levonorgestrel) dosage forms

                    Typical dosing for Mirena IUD (levonorgestrel)

                    Your provider will place Mirena IUD (levonorgestrel) inside the uterus at their office.

                    • Prevent pregnancy: Mirena IUD (levonorgestrel) will stay in place for up to 8 years. Then, your provider will remove the IUD at their office.

                    • Heavy menstrual bleeding: Mirena IUD (levonorgestrel) will stay in place for up to 5 years. Then, your provider will remove the IUD at their office.

                    interactions

                    Interactions between Mirena IUD (levonorgestrel) and other drugs

                    Mirena IUD (levonorgestrel) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Mirena IUD (levonorgestrel). Please note that only the generic name of each medication is listed below.

                    Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

                    Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                    Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                    Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                    contraindications-icon

                    Mirena IUD (levonorgestrel) contraindications

                    Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Mirena IUD (levonorgestrel) will not be safe for you to take.
                    • Pregnancy or suspicion of pregnancy

                    • Use as emergency contraception

                    • Certain abnormal uterine anatomy

                    • Acute pelvic inflammatory disease (PID) or a history of PID

                    • Postpartum endometritis or infected abortion in the past 3 months

                    • Uterine or cervical cancer

                    • Breast cancer or other progestin-sensitive cancer

                    • Uterine bleeding without a known cause

                    • Untreated inflammation of the cervix or vagina, or other lower genital tract infections

                    • Liver disease or liver tumor

                    • A previous intrauterine device (IUD) that hasn't been removed

                    alternatives

                    What are alternatives to Mirena IUD (levonorgestrel)?

                    There are a number of medications that your doctor can prescribe in place of Mirena IUD (levonorgestrel). Compare a few possible alternatives below.
                    Mirena IUD (levonorgestrel)
                    Used for:
                    Used for:
                    • To prevent pregnancy

                    Used for:
                    • To prevent pregnancy

                    latest news

                    What is the latest news about Mirena IUD (levonorgestrel)?

                    Get savings updates for Mirena IUD (levonorgestrel)

                    Receive price alerts, news, and other messages from GoodRx about Mirena IUD (levonorgestrel) and other healthcare topics and relevant savings offers.

                    By providing your email, you consent to receive marketing communications from GoodRx, which may include content and/or data related to men’s health, women's health, reproductive care, or sexual health. You agree to the GoodRx Terms of Use and acknowledge the Privacy Policy. You can unsubscribe at any time.

                    References

                    Best studies we found

                    American College of Obstetricians and Gynecologists. (2023). Postpartum birth control.

                    Bayer. (2023). IUDs and other birth control options.

                    Bayer HealthCare Pharmaceuticals Inc. (2022). Mirena- levonorgestrel intrauterine device [package insert]. DailyMed.

                    View All References (1)

                    Centers for Disease Control and Prevention. (2023). Contraception.

                    GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
                    Was this page helpful?

                    Browse medications

                    View All

                    Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.