M-End Dmx
M-END DMX is a combination of three medications: dexbrompheniramine (an antihistamine), dextromethorphan (a cough suppressant), and pseudoephedrine (a decongestant). M-END DMX is available over the counter and is used to treat symptoms from allergies and the common cold. It's a liquid that people 6 years of age and older can take by mouth every 6 hours when they need symptom relief. M-END DMX can make you sleepy, so it's best to avoid alcohol when you're taking this medication. Other side effects include dizziness and dry mouth.
What is M-END DMX?
What is M-END DMX used for?
Short-term relief of symptoms from allergies and the common cold:
- Cough from throat and lung irritation
- Runny nose
- Sneezing
- Itchy or watery eyes
- Itching of the nose or throat
- Stuffy nose (nasal congestion)
How M-END DMX works
M-END DMX is a combination of three medications that work together to relieve allergy and common cold symptoms.
- Dexbrompheniramine is an antihistamine. It blocks a natural substance in your body called histamine that normally causes allergy and common cold symptoms. By blocking histamine, dexbrompheniramine lessens inflammation (swelling) and relieves runny or itchy nose, sneezing, and watery eyes.
- Dextromethorphan is a cough suppressant. It works in the brain to lower your urge to cough.
- Pseudoephedrine is a decongestant that clears your sinuses to relieve sinus pressure.
Drug facts
| Common Brands | M-END DMX |
|---|---|
| Drug Class | Antihistamine / Cough suppressant / Decongestant |
| Controlled Substance Classification | Controlled in some states. See FAQs below. |
| Generic Status | No lower-cost generic available |
| Availability | Over-the-counter |
Side effects of M-END DMX
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Less Common Side Effects
M-END DMX serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Excessive sleepiness or dizziness
- Serotonin syndrome: fast heart rate, sweating, muscle stiffness or spasms, high fever, confusion
- Taking too much medication: confusion, vision changes, heart rhythm problems, hallucinations
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Pros and cons of M-END DMX
Pros
- Convenient to take three medications in a single product
- Typically starts working within 30 minutes to an hour
- Can relieve a wide variety of allergy and common cold symptoms
- Available over the counter
- Available as a fruit-flavored liquid for better taste
Cons
- Might have to take as often as every 6 hours to relieve symptoms
- More difficult to customize the dose since M-END DMX is a fixed combination of three medications
- Available as a brand-name product only
- Only available as a liquid
- Might not be the best choice for people over 65 years old; people with glaucoma; or people with breathing, heart, or urinary problems
Pharmacist tips for M-END DMX
- You can take M-END DMX with or without food. If it upsets your stomach, try taking the medication with food.
- You can take M-END DMX as needed for cold and allergy symptoms. But it's recommended you take the medication on a scheduled basis according to the package instructions while you're having symptoms to get the most relief.
- Use a medication dose cup or an oral syringe to measure our your dose of M-END DMX. Ask your pharmacy to provide you with extras just in case the product doesn't have one or just in case you lose it. Don't use household spoons; they might not be accurate and using them might cause you to take the wrong dose.
- M-END DMX can keep you awake or make you sleepy or dizzy. Don't drive until you know how the medication affects you.
- Don't drink alcohol or take M-END DMX with other medications that cause sleepiness, such as opioids or benzodiazepines. This can make dizziness or sleepiness from the medications more intense and raise your risk for accidental injuries.
- While M-END DMX usually makes adults sleepy, it's possible for children who take the medication to become overly excited or energetic. Speak to a pediatrician if this happens to your child.
- Stop using M-END DMX and contact your primary care provider if your cough or congestion lasts longer than a week; keeps coming back; or occurs with a fever, rash, or headache. Also call your primary care provider if you start to feel nervous or dizzy, have trouble sleeping, or have any other new symptoms. You might need to get examined by your primary care provider.
- Don't start any new medications while you're taking M-END DMX — especially other antihistamines, cough suppressants, or decongestants — without talking to your primary care provider or pharmacist first. Taking certain medications with M-END DMX can raise your risk for serious side effects, including daytime sleepiness, dizziness, high blood pressure, and fast heart rate.
- Don't use M-END DMX if you're currently taking or have taken a monoamine oxidase inhibitor (MAOI) in the last 2 weeks. This combination can raise your risk for serious side effects like serotonin syndrome and dangerously high blood pressure. Ask your pharmacist for other options to treat your cough, congestion, or allergy symptoms.
Risks and warnings for M-END DMX
M-END DMX can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Worsening of certain medical conditions
- Risk factors: Cough from smoking, asthma, or emphysema | Mucus-producing cough | Breathing problems | Heart disease or high blood pressure | Thyroid problems | High blood sugar (diabetes) | Glaucoma | Urinary problems
Let your primary care provider and pharmacist know about all the medical conditions you have before you start taking M-END DMX. Ask them whether this medication is safe for you to take.
People who are 65 years of age or older might feel side effects from M-END DMX more intensely. In addition, M-END DMX might worsen certain medical conditions, such as high blood pressure and glaucoma. This medication also might not be appropriate for your condition. For example, you might need other treatment if you have a cough that's lasted for a long time; a cough that occurs with smoking, asthma, or emphysema; or a cough with a lot of mucus.
Serotonin syndrome
- Risk factors: Taking a monoamine oxidase inhibitor (MAOI) 2 weeks before starting M-END DMX | Taking other medications that raise serotonin levels in the body
Serotonin syndrome is a rare, but potentially life-threatening condition that happens when there's too much serotonin in the brain. Serotonin is one of the chemicals in your brain responsible for your mood.
It's possible for dextromethorphan (one of the ingredients in M-END DMX) to raise your serotonin levels. The risk for serotonin syndrome goes up if you take M-END DMX with other medications that also affect serotonin levels, such as antidepressants, MAOIs, and migraine medications called triptans. Be sure your primary care provider and pharmacist know about all the medications you take and plan to take (including over-the-counter medications and supplements).
Get medical help right away if you have symptoms of serotonin syndrome, such as fast heart rate, sweating, muscle stiffness or spasms, high fever, and confusion.
Accidentally taking too much medication
M-END DMX contains an antihistamine (dexbrompheniramine), cough suppressant (dextromethorphan), and a decongestant (pseudoephedrine). These ingredients can all be found in many other over-the-counter products.
The risk of taking too much of any particular ingredient is higher if you use more than one product that contains an antihistamine, cough suppressant, or a decongestant. This can be dangerous and cause serious side effects, such as very high blood pressure, daytime sleepiness, changes in heart rhythm, and hallucinations (seeing things that aren't real).
Ask your primary care provider or pharmacist if you're not sure whether you're taking a medication that has the same or similar ingredients as M-END DMX. Get medical help or contact a Poison Control Center at 1-800-222-1222 right away if you think you or a loved one accidentally took too much medication.
M-END DMX dosage
Ml of oral solution| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 0.667mg/10mg/20mg/5ml | 300 ml | $28.69 | $0.10 |
Typical dosage for M-END DMX
Each 5 mL (1 teaspoonful) of M-END DMX contains 0.667 mg of dexbrompheniramine, 10 mg of dextromethorphan, and 20 mg of pseudoephedrine.
- Ages 12 years or older: The typical dose is 15 mL (3 teaspoonfuls) by mouth every 6 hours when you have symptoms. Don't use more than 4 doses (60 mL or 12 teaspoonfuls) in a 24-hour period.
- Age 6 years to under 12 years: The typical dose is 7.5 mL (1.5 teaspoonfuls) by mouth every 6 hours when your child has symptoms. Don't use more than 4 doses (30 mL or 6 teaspoonfuls) in a 24-hour period.
- Age under 6 years: Ask your child's pediatrician.
How much does M-END DMX cost?
$28.69
M-END DMX contraindications
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because M-END DMX will not be safe for you to take.
- Currently take or have taken a monoamine oxidase inhibitor (MAOI) in the last 2 weeks
What are alternatives to M-END DMX?
Short-term relief of symptoms from allergies and the common cold:
