The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Lightheadedness
- Dizziness
- Sleepiness
- Nausea
- Vomiting
Less Common Side Effects
- Constipation
- Itching
- Headache
- Tiredness
- "Brain fog"
- Stomach pain
- Changes in blood pressure
Lortab serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Dangerously slow breathing: trouble breathing; bluish-colored lips, fingers, or toes
- Accidentally taking too much (overdose): not responding to sound or touch, slowed breathing, extreme sleepiness, cold or clammy skin, slow heartbeat, upper right-sided stomach pain, dark urine, yellowing of your skin or eyes
- Opioid withdrawal: anxiety, suicidal thoughts, restlessness, runny nose, yawning, sweating, chills, wide pupils, irritability
- Serious allergic reaction or skin reaction: rash, hives, blistering or peeling skin, shortness of breath, fast heartbeat, dizziness, feeling warm suddenly
Source: DailyMed
More on Lortab side effects

The following Lortab side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Dizziness
lightheadedness
Incidence not known
Back, leg, or stomach pains
black, tarry stools
bleeding gums
blood in the urine or stools
blood in vomit
bluish lips or skin
chills
choking
dark urine
decrease in the frequency of urination
decrease in urine volume
difficult or trouble breathing
difficulty in passing urine (dribbling)
difficulty with swallowing
fast heartbeat
fever with or without chills
general body swelling
general feeling of tiredness or weakness
headache
hoarseness
irregular, fast or slow, or shallow breathing
light-colored stools
loss of appetite
lower back or side pain
nosebleeds
not breathing
painful or difficult urination
pale or blue lips, fingernails, or skin
pinpoint red spots on the skin
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
severe or continuing stomach pain
sore tongue
sores, ulcers, or white spots on the lips or in the mouth
tightness in the chest
unable to speak
unusual bleeding or bruising
unusual tiredness or weakness
upper right abdominal or stomach pain
vomiting
yellow eyes and skin
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Bloody or cloudy urine
change in consciousness
chest pain or discomfort
cold and clammy skin
decreased awareness or responsiveness
extreme drowsiness
general feeling of discomfort or illness
increased sweating
irregular heartbeat
lightheadedness, dizziness, or fainting
loss of consciousness
no blood pressure or pulse
no muscle tone or movement
not breathing
severe sleepiness
slow or irregular heartbeat
stopping of heart
sudden decrease in the amount of urine
unpleasant breath odor
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Drowsiness
relaxed and calm feeling
sleepiness
Incidence not known
Belching
changes in mood
difficulty having a bowel movement
fear or nervousness
feeling of indigestion
hearing loss
impaired hearing
pain in the chest below the breastbone
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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