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Lortab

Lortab Side Effects

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on April 8, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Lightheadedness
  • Dizziness
  • Sleepiness
  • Nausea
  • Vomiting

Less Common Side Effects

  • Constipation
  • Itching
  • Headache
  • Tiredness
  • "Brain fog"
  • Stomach pain
  • Changes in blood pressure

Lortab serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Dangerously slow breathing: trouble breathing; bluish-colored lips, fingers, or toes
  • Accidentally taking too much (overdose): not responding to sound or touch, slowed breathing, extreme sleepiness, cold or clammy skin, slow heartbeat, upper right-sided stomach pain, dark urine, yellowing of your skin or eyes
  • Opioid withdrawal: anxiety, suicidal thoughts, restlessness, runny nose, yawning, sweating, chills, wide pupils, irritability
  • Serious allergic reaction or skin reaction: rash, hives, blistering or peeling skin, shortness of breath, fast heartbeat, dizziness, feeling warm suddenly

Source: DailyMed

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The following Lortab side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Dizziness

lightheadedness

Incidence not known

Back, leg, or stomach pains

black, tarry stools

bleeding gums

blood in the urine or stools

blood in vomit

bluish lips or skin

chills

choking

cough

dark urine

decrease in the frequency of urination

decrease in urine volume

difficult or trouble breathing

difficulty in passing urine (dribbling)

difficulty with swallowing

fast heartbeat

fever

fever with or without chills

general body swelling

general feeling of tiredness or weakness

headache

hoarseness

irregular, fast or slow, or shallow breathing

light-colored stools

loss of appetite

lower back or side pain

nausea

nosebleeds

not breathing

painful or difficult urination

pale or blue lips, fingernails, or skin

pinpoint red spots on the skin

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

severe or continuing stomach pain

skin rash, hives, or itching

sore throat

sore tongue

sores, ulcers, or white spots on the lips or in the mouth

tightness in the chest

unable to speak

unusual bleeding or bruising

unusual tiredness or weakness

upper right abdominal or stomach pain

vomiting

yellow eyes and skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Bloody or cloudy urine

change in consciousness

chest pain or discomfort

cold and clammy skin

decreased awareness or responsiveness

extreme drowsiness

general feeling of discomfort or illness

increased sweating

irregular heartbeat

lightheadedness, dizziness, or fainting

loss of consciousness

no blood pressure or pulse

no muscle tone or movement

not breathing

severe sleepiness

slow or irregular heartbeat

stopping of heart

sudden decrease in the amount of urine

unpleasant breath odor

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Drowsiness

relaxed and calm feeling

sleepiness

Incidence not known

Belching

changes in mood

difficulty having a bowel movement

fear or nervousness

feeling of indigestion

hearing loss

impaired hearing

pain in the chest below the breastbone

unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.

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