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Liothyronine

Liothyronine Side Effects

Hope Chang, PharmD, AAHIVPAllison Gourley, PharmD
Reviewed by Hope Chang, PharmD, AAHIVP, Allison Gourley, PharmD
Last reviewed on September 12, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Side effects are typically signs of having too much thyroid hormone in the body.

  • Shakiness
  • Fast or irregular heartbeat
  • Fever
  • Sweating
  • Easily feel hot
  • Hair loss
  • Larger appetite
  • Diarrhea
  • Weight loss
  • Weak muscles
  • Fatigue
  • Nervousness or anxiety
  • Irritability
  • Trouble sleeping
  • Trouble breathing

Liothyronine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Heart problems (e.g., heart attack): chest pain; shortness of breath; feeling weak; breaking into a cold sweat; pain that spreads to the jaw, neck, back, shoulders, arms
When do Liothyronine possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Symptoms of too much thyroid hormone
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Liothyronine side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Anxiety

arm, back, or jaw pain

blurred or double vision

chest pain or discomfort

chest tightness or heaviness

crying

decreased bone mineral density

decreased urine output

delusions of persecution, mistrust, suspiciousness, or combativeness

diarrhea

difficulty breathing

dilated neck vein

dizziness

excessive

sweating

extreme tiredness or weakness

eye pain

fainting

false or unusual sense of well-being

fast, pounding, or irregular heartbeat or pulse

feeling of discomfort

feeling of unreality

fever

headache

heat intolerance

impaired fertility

increased appetite

increased blood pressure

irregular breathing

irritability

itching, skin rash

joint swelling

limp pain in the hip or knee

menstrual changes

mental depression

muscle aches, weakness, or cramps

nausea

nervousness

pain or discomfort in the arms, jaw, back, or neck

quick to react or overreact emotionally

rapidly changing moods

restlessness

sense of detachment from self or body

severe headache

slow heartbeat

stomach cramps

swelling of the face, fingers, feet, or lower legs

swollen lymph glands

tremors

trouble sitting still

trouble sleeping

vomiting

weight gain or loss

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Cold, clammy skin

confusion about identity, place, and time

difficulty in speaking

dizziness

double vision

fast, weak pulse

headache

inability to move the arms, legs, or facial muscles

inability to speak

lightheadedness

loss of consciousness

nervousness

seizure

sensitivity to heat

slow speech

sweating

trouble sleeping

weight loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Feeling of warmth

hair loss

redness of the face, neck, arms, and occasionally, upper chest

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Hope Chang is a freelance writer and content reviewer for GoodRx. She attended Howard University College of Pharmacy in Washington, D.C. and completed post-graduate residency training at the University of California, Davis Medical Center.
Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.

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