provider image
Welcome! You’re in GoodRx for healthcare professionals. Now, you’ll enjoy a streamlined experience created specifically for healthcare professionals.
Skip to main content
Isradipine Coupon - Isradipine 5mg capsule

isradipine

Generic Dynacirc
Used for Hypertension, Raynaud's Phenomenon
Used for Hypertension, Raynaud's Phenomenon

Isradipine is used to lower blood pressure. The long-acting version and the brand name version of isradipine have been discontinued. But the generic is still available as a capsule that's taken by mouth, typically twice daily. Like all calcium channel blockers, some common side effects of isradipine include swelling, dizziness, and headache.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Allison Gourley, PharmD
Last reviewed on June 8, 2023
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Isradipine?

What is Isradipine used for?

  • High blood pressure (hypertension)

How Isradipine works

Isradipine is a calcium channel blocker. It works by relaxing your blood vessels to lower your blood pressure. This also helps your heart to get more oxygen so it doesn't need to work as hard to pump, which can help with chest pain.

Drug Facts

Common BrandsDynacirc (brand no longer available)
Drug ClassCalcium channel blocker (CCB)
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
coupon-save-icon

Get your GoodRx coupon

Avg retail price
$863.57(save 86.25%)
GoodRx discount
$118.70
See prices
basics-icon

What are the side effects of Isradipine?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache (14%)
  • Swelling in the legs, feet, or hands (7%)
  • Dizziness (7%)

Other Side Effects

  • Fast heartbeat
  • Tiredness
  • Flushing
  • Chest pain
  • Trouble breathing
  • Nausea

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Dangerously low blood pressure: dizziness, lightheadedness, pale skin, feeling faint or fainting

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bloating or swelling of face, arms, hands, lower legs, or feet

tingling of hands or feet

unusual weight gain or loss

Less common

Chest pain

difficult or labored breathing

dizziness

fast, irregular, pounding, or racing heartbeat or pulse

feeling of warmth

full or bloated feeling

nausea

pressure in the stomach

redness of the face, neck, arms and occasionally, upper chest

shortness of breath

swelling of abdominal or stomach area

tightness in chest

unusual tiredness or weakness

vomiting

wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of Overdose

Blurred vision

confusion

dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

flushing

sweating

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Headache

Less common

Diarrhea

difficulty having a bowel movement (stool)

rash

stomach soreness or discomfort

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Isradipine

thumbs-up

Pros

Lowers risk of heart attack and stroke caused by high blood pressure

Can be used in combination with a thiazide-type water pill like hydrochlorothiazide

Taken by mouth

thumbs-down

Cons

Can cause headache and swelling in the legs and feet

Typically taken twice daily

Only available as a capsule

pharmacist-tips

Pharmacist tips for Isradipine

pharmacist

  • Take isradipine with or without food at any time of day. If it hurts your stomach, try taking it with food to help.

    • It's recommended that you check your blood pressure at home, record it, and bring your log to your medical appointments. Discuss with your provider how well isradipine is working for you.

      • Mark your calendar with your appointments to see your provider and to get any blood work done during treatment with isradipine. Your provider might measure your blood pressure, blood potassium level, and kidney function to keep track of how well the medication is working and how safe it is for you.

        • You might feel dizzy when you start taking isradipine and when your provider raises your dose. This side effect should lessen over time as you continue taking the medication and your body gets used to your new blood pressure.

          • Some people experience swelling in their feet, ankles, legs, or hands when they take isradipine. Talk with your provider if you notice swelling or if the swelling becomes too bothersome. They might recommend tips to ease the swelling, such as sitting or lying down with your legs raised or wearing compression socks.

            • If you accidentally miss a dose of isradipine, take it as soon as you remember. But if more than 12 hours have passed since the time you were scheduled to take your dose, then skip that dose and take your next dose at your regularly scheduled time. Don't take 2 doses of isradipine at the same time to make up any missed doses.

              faqs

              Frequently asked questions about Isradipine

              How long does it take for isradipine to work?
              Isradipine starts to lower blood pressure in about 2 to 3 hours after you take it. But, it could take up to 2 to 4 weeks to get the full effects of the medication. If you don't see a change in your blood pressure right after you start isradipine, it doesn't mean this medication isn't working. Talk to your provider if you're concerned about how well isradipine is working for you.
              How do I know isradipine is working for me?
              You can track how well isradipine is working for you by checking your blood pressure regularly at home. Write down your blood pressure readings and bring them to your appointments with your provider so you can discuss how well isradipine is working for you. Even though you can't directly feel the effects of blood pressure medications like isradipine, make sure to continue taking isradipine unless your provider specifically told you it was safe to stop. Well-controlled blood pressure helps prevent severe and life-threatening health problems, such as heart attack, stroke, and heart failure.
              Do you have to slowly stop taking isradipine?
              Yes, it's recommended to lower the dose slowly before stopping isradipine. This is to help prevent withdrawal symptoms (e.g., high blood pressure, chest pain, fast heartbeat) from isradipine. If you're wanting to stop taking isradipine, contact your provider to come up with a plan to stop the medication safely.
              What is the difference between isradipine and amlodipine (Norvasc)?
              Both isradipine and amlodipine are calcium channel blockers that work well for treating high blood pressure, but amlodipine (Norvasc) is also used for people with coronary artery disease (clogged arteries in the heart). Isradipine is typically taken twice per day, whereas the dosing for amlodipine (Norvasc) is usually once per day. Amlodipine (Norvasc) is available as liquid and tablet, whereas isradipine is only available as a capsule. Talk with your provider if you've more questions about the difference between isradipine and amlodipine (Norvasc).
              Can I use isradipine if I'm pregnant?
              If you're pregnant, talk to your provider. There isn't a lot of data from clinical studies available on the safety of isradipine during pregnancy. A small study showed babies born to females who took isradipine weren't harmed. Because treating high blood pressure during pregnancy is very important for the health of you and your baby, your provider will want to discuss with you about safer options to manage your blood pressure.
              Can I use isradipine if I'm breastfeeding?
              Let your provider know if you're breastfeeding or thinking about breastfeeding. There haven't been any studies on the safety of isradipine in nursing babies, so your provider will likely recommend a different blood pressure medication during this time.
              GoodRxEducationalIcon

              How to save using GoodRx

              Compare Prices
              1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
              Select your free coupon
              2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
              Show coupon to your pharmacist
              3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
              Get free couponLearn more
              warings-icon

              What are the risks and warnings for Isradipine?

              Isradipine can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

              risk-warning

              Low blood pressure

              Isradipine can cause your blood pressure to drop too much, which can make you feel dizzy, tired, or lightheaded. But serious dizziness is pretty rare. These side effects typically happen when you first start the medication or when your provider raises the dose. If your blood pressure drops too much and you feel too dizzy, make sure to sit down slowly while holding onto something. Let your provider know because they might need to adjust the dose of your medication. If you fall and hit your head, get medical help right away.

              risk-warning

              Risk of worsening heart failure

              • Risk factors: Taking a beta-blocker at the same time

                If you have heart failure, make sure to follow-up with your provider regularly to monitor your heart health. Isradipine can slow your heart rate and make it more difficult for your heart to pump blood throughout your body, which can worsen heart failure. Your risk for this side effect is higher if you're taking a beta blocker (medications that end with -olol). Let your provider know if you notice symptoms such as trouble breathing, tiredness, and swelling in the hands or feet.

                dosage

                Isradipine dosage forms

                The average cost for 180 capsules of 5mg of Isradipine is $188.44 with a free GoodRx coupon. This is 78.18% off the average retail price of $863.57.
                capsule
                Capsule
                DosageQuantityPrice as low asPrice per unit
                2.5mg180 capsules$118.70$0.66
                5mg180 capsules$188.44$1.05

                Typical dosing for Isradipine

                The typical starting dose is 2.5 mg by mouth twice daily. If needed, your provider will raise the dose slowly. The typical maintenance dose is 10 mg total daily. The maximum dose is 20 mg daily.

                interactions

                Interactions between Isradipine and other drugs

                Isradipine may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Isradipine. Please note that only the generic name of each medication is listed below.

                Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                drug-cost

                How much does Isradipine cost?

                To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
                Isradipine (generic)
                GoodRx lowest price

                $118.70

                (save 86.25%)
                View prices & coupons
                alternatives

                What are alternatives to Isradipine?

                There are a number of medications that your doctor can prescribe in place of Isradipine. Compare a few possible alternatives below.
                Isradipine
                Used for:

                • High blood pressure (hypertension)

                $118.70 Lowest GoodRx priceView Prices
                Amlodipine (Norvasc)
                Used for:

                • High blood pressure

                • Clogged arteries in the heart (coronary artery disease)

                $5.70 Lowest GoodRx priceView Prices
                Nifedipine ER (Procardia XL)
                Used for:

                • Chest pain (angina)

                • High blood pressure (hypertension) - extended-release tablets only

                $9.30 Lowest GoodRx priceView Prices
                images

                Isradipine images

                Brown Logo Is 5 And Abrika 109 Abrika 109 - Isradipine 5mg Capsule
                This medicine is Brown Capsule Imprinted With "Abrika 109 Abrika 109" And "Logo Is 5".Brown Logo Is 5 And Abrika 109 Abrika 109 - Isradipine 5mg Capsule
                Pink A-264 A-264 - Isradipine 5mg Capsule
                This medicine is Pink Capsule Imprinted With "A-264 A-264".Pink A-264 A-264 - Isradipine 5mg Capsule
                Pink A-264 A-264 - Isradipine 5mg Capsule
                This medicine is Pink Capsule Imprinted With "A-264 A-264".Pink A-264 A-264 - Isradipine 5mg Capsule

                Get savings updates for Isradipine

                Receive price alerts, news, and other messages from GoodRx about Isradipine and other healthcare topics and relevant savings offers.

                By providing your email, you consent to receive marketing communications from GoodRx, which may include content and/or data related to men’s health, women's health, reproductive care, or sexual health. You agree to the GoodRx Terms of Use and acknowledge the Privacy Policy. You can unsubscribe at any time.

                References

                Best studies we found

                Drugs and Lactation Database (LactMed). (2018). Isradipine. National Institute of Child Health and Human Development.

                Epic Pharma, LLC. (2021). Isradipine capsule [package insert]. DailyMed.

                Feiks, A., et al. (1991). Influence of isradipine on the maternal and fetal cardiovascular system in hypertensive disorders in pregnancy. American Journal of Hypertension.

                GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
                Was this page helpful?

                Browse medications

                View All

                Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.