The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
The following side effects were reported by people taking Inlyta (axitinib) by itself. Inlyta (axitinib) is often given along with other anticancer medications, so side effects might differ.
- Diarrhea (55%)
- High blood pressure (40%)
- Tiredness (39%)
- Less appetite (34%)
- Nausea (32%)
- Hoarseness (31%)
- Hand-foot skin reaction (27%)
- Weight loss (25%)
- Vomiting (24%)
- Weakness (21%)
- Constipation (20%)
Less Common Side Effects
- Inflammation in the mouth or mouth sores
- Taste changes
- Upset stomach
- Belly pain
- Joint pain
- Pain in arms or legs
- Shortness of breath
- Cough
- Headache
- Rash
- Dry skin
- Hypothyroidism (low thyroid hormone levels)
Inlyta serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Dangerously high blood pressure: headache, confusion, blurry vision, chest pain, nausea, vomiting
- Blood clot in the lungs: cough, chest pain, trouble breathing, racing heart
- Blood clot in the leg: leg cramp, swelling, pain, muscle tightness
- Stroke: sudden numbness or weakness in the arm, leg, or face; confusion; headache; trouble seeing or walking
- Heart problems (e.g., heart attack, heart failure): shortness of breath, chest pain, sweating, weakness, tiredness, dizziness, nausea, swelling in feet and legs, sudden weight gain
- Serious bleeding: unusual bleeding, bleeding that’s difficult to stop, easy bruising, blood in urine or stool, black or tarry stool, vomiting blood, stomach cramps
- Tears in the gut: fever, chills, intense stomach pain or cramps, bloating, vomiting blood, red or black stool
Source: DailyMed
The following Inlyta side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Bleeding gums
bloody nose
blurred vision
clay colored stools
cloudy urine
confusion
coughing up blood
decreased urination
depressed mood
difficult or labored breathing
difficulty with swallowing
dizziness
dry skin and hair
fainting
feeling cold
headache
hoarseness or husky voice
incoherent speech
increased menstrual flow or vaginal bleeding
increased urination
itching skin or rash
lightheadedness
loss of appetite
metallic taste
muscle cramps, stiffness, or weakness
nervousness
nosebleeds
paralysis
pounding in the ears
rapid breathing
red or black, tarry stools
red or dark brown urine
redness, swelling, or pain of the skin
scaling of the skin on the hands and feet
slow or fast heartbeat
stomach pain or tenderness
sunken eyes
swelling of the feet or lower legs
thirst
tightness in the chest
tingling of the hands and feet
ulceration of the skin
unusual tiredness or weakness
vomiting
weight gain or loss
wrinkled skin
yellow eyes or skin
Less common
bleeding from the gums or nose
bleeding from the rectum
bloody, black or tarry stools
change in vision
chest pain or discomfort
extreme drowsiness
inability to speak
indigestion
numbness or tingling in the face, arms, hands, or legs
pain in the chest, groin, or legs
pain or discomfort in the arms, jaw, back, or neck
pain, redness, or swelling in the arm or leg
pale skin
ringing in the ears
seizures
sensitivity to heat
severe headaches of sudden onset
severe stomach pain, cramping, or burning
slurred speech
sores, ulcers, or white spots on the lips, tongue, or inside the mouth
sudden loss of coordination
sudden onset of slurred speech
sudden vision changes
sweating
temporary blindness
trouble sleeping
trouble speaking, thinking, or walking
troubled breathing with exertion
uncomfortable swelling around the anus
unusual bleeding or bruising
vomiting of material that looks like coffee grounds
weakness in the arm or leg on one side of the body
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Belching
change in taste
cracked lips
decreased appetite
difficulty with moving
joint pain or swelling
lack or loss of strength
loss of taste
muscle aches or pain
pain in the arms or legs
stomach discomfort or upset
swelling or inflammation of the mouth
upper stomach pain
voice changes
Less common
Burning sensation of the tongue
continuous ringing or buzzing or other unexplained noise in the ears
flushing or redness of the skin
hearing loss
thinning of the hair
unusually warm skin
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
