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Hyoscyamine

Hyoscyamine Dosage

Robert Chad Hakim, PharmD, BCCCPDaisy Chau, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Daisy Chau, PharmD
Last reviewed on April 20, 2026

The average cost for 30 sublingual tablets of 0.125mg of Hyoscyamine is $12.83 with a free GoodRx coupon. This is 59.51% off the average retail price of $31.69.

sublingual tabletSublingual tablet

Dosage

Quantity

Price as low as

Price per unit

0.125mg

30 sublingual tablets

$12.83

$0.43

tabletTablet

Dosage

Quantity

Price as low as

Price per unit

0.125mg

30 tablets

$12.76

$0.43

ml of elixirMl of elixir

Dosage

Quantity

Price as low as

Price per unit

0.125mg/5ml

120 ml

$19.88

$0.17

orally disintegrating tabOrally disintegrating tab

Dosage

Quantity

Price as low as

Price per unit

0.125mg

30 orally disintegrating tabs

$12.22

$0.41

dropperDropper

Dosage

Quantity

Price as low as

Price per unit

15ml of 0.125mg/ml

1 dropper

$16.20

$16.20

20ml of 0.125mg/ml

1 dropper

$19.94

$19.94

Typical dosage for Hyoscyamine

Hyoscyamine comes in many different forms, including immediate-release (IR) tablets, extended-release (ER) tablets, orally disintegrating tablets, and liquid solutions. Follow your prescriber’s instructions for your specific product.

Some examples include:

  • Hyoscyamine 0.125 mg immediate-release (IR) tablet:

    • Age 12 years or older: The typical dose is 1 to 2 tablets every 4 hours or as needed. The maximum dose is 12 tablets within 24 hours.
    • Age 2 to under 12 years (IR tablet only): The typical dose is half a tablet to 1 tablet every 4 hours or as needed. The maximum dose is 6 tablets within 24 hours.
  • Hyoscyamine 0.375 mg extended-release (ER) tablets:

    • Age 12 years or older: The typical dose is 1 to 2 tablets by mouth every 12 hours. The maximum dose is 4 tablets within 24 hours.
  • Hyoscyamine 0.125 mg/1 mL liquid solution:

    • Age 12 years or older: The typical dose is 1 to 2 mL by mouth every 4 hours or as needed. The maximum dose is 12 mL within 24 hours.
    • Age 2 to under 12 years: The typical dose is ¼ to 1 mL by mouth every 4 hours or as needed. Do not take more than 6 mL within 24 hours.
    • Age under 2 years: The dose depends on your child's weight. In general, the typical dose ranges from 4 drops to 8 drops by mouth every 4 hours or as needed.

There's also an injectable form that's used for people in the hospital who can't take the medication by mouth.

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