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Gilotrif
Specialty Drug

Afatinib

AFATINIB is a medicine that targets proteins in cancer cells and stops the cancer cells from growing. It is used to treat non-small cell lung cancer. Compare kinase inhibitors.
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Gilotrif Side Effects

What should I watch for?

Visit your doctor for regular check ups. Report any side effects. Continue your course of treatment unless your doctor tells you to stop. You will need blood work done while you are taking this medicine.

If you experience any of the following, contact your health care provider: eye irritation; rash; severe or continuing diarrhea, nausea, decreased appetite, or vomiting; or if your breathing gets worse or you develop shortness of breath or cough.

Do not become pregnant while taking this medicine or for 2 weeks after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 2 weeks after the last dose.

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Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bloody or cloudy urine

burning, dry, or itching eyes

diarrhea

difficult, burning, or painful urination

discharge or excessive tearing

fever

frequent urge to urinate

redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

redness, swelling, or pain of the skin

scaling of the skin on the hands and feet

tingling of the hands and feet

ulceration of the skin

Less common

Cough

difficult breathing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Abdominal or stomach pain

dizziness

headache

lack or loss of strength

nausea

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Blemishes on the skin

canker sores

chapped, red, or swollen lips

decreased appetite

decreased weight

dry skin

itching skin or rash

loosening of the fingernails

nosebleeds

pimples

redness or soreness around the fingernails

runny nose

scaling, redness, burning, pain, or other signs of inflammation of the lips

sores, ulcers, or white spots on the lips or tongue or inside the mouth

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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