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Dotremin

folic acid / cholecalciferol
Used for Folate Deficiency, Vitamin D Deficiency

Dotremin (folic acid / cholecalciferol) is a combination supplement containing cholecalciferol (vitamin D3) and folic acid for people with low levels of both vitamins. Dotremin (folic acid / cholecalciferol) is a dietary supplement that requires a prescription from a provider.

Reviewed by:Last reviewed on October 20, 2022
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What is Dotremin (folic acid / cholecalciferol)?

What is Dotremin (folic acid / cholecalciferol) used for?

  • Low vitamin D and folic acid levels

How Dotremin (folic acid / cholecalciferol) works

Dotremin (folic acid / cholecalciferol) is a combination of two vitamins that each have important roles and functions in your body.

  • Cholecalciferol or vitamin D3 helps your body absorb calcium in order to build strong bones and teeth. It also plays an important role in your overall health.
  • Folic acid is also known as vitamin B9. It helps your body make genetic material (DNA) and new red blood cells to prevent anemia (low red blood cell count).

Drug facts

Common BrandsDotremin, Folditam, Foltamin, Folvite D, Folixate
Drug ClassDietary supplement
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Side effects of Dotremin (folic acid / cholecalciferol)

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

See Risks and Warnings

Dotremin (folic acid / cholecalciferol) serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reaction: rash; hives; difficulty breathing; swelling of face, mouth, tongue, or throat
  • Toxicity from taking too much: nausea, vomiting, constipation, loss of appetite, feeling tired

Source: DailyMed

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Pros and cons of Dotremin (folic acid / cholecalciferol)

Pros

  • Conveniently combines two medications in a single pill
  • Can be used in pregnant women
  • Can be taken with or without food

Cons

  • Difficult to customize the dose since each pill contains two medications
  • Brand name only, which can be expensive
  • Shouldn't be given to a child unless a provider said it's safe to do so
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Pharmacist tips for Dotremin (folic acid / cholecalciferol)

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  • Take Dotremin (folic acid / cholecalciferol) with or without food. If it's hurting your stomach, try taking it with food to help.
  • Tell your provider or pharmacist about all the medications and supplements you're taking before starting Dotremin (folic acid / cholecalciferol) to make sure there are no interactions. In some cases, you might need your medication doses adjusted if your provider finds a potentially harmful drug interaction with Dotremin (folic acid / cholecalciferol).
  • Store Dotremin (folic acid / cholecalciferol) at room temperature and away from children. If your child accidentally took Dotremin (folic acid / cholecalciferol), get medical help or call the Poison Control Center at 1-800-222-1222 right away.
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Common questions about Dotremin (folic acid / cholecalciferol)

There are many different brand names of folic acid-cholecalciferol products, including Dotremin, Folditam, Foltamin, and Folvite D. While all brands have 1 mg of folic acid, the amount of cholecalciferol (vitamin D3) differs among the products. Your provider can help you decide the best product for your nutritional needs.

No, don't take other supplements with folic acid or vitamin D while you're taking Dotremin (folic acid / cholecalciferol) unless your provider specifically told you to do so. Too much folic acid can potentially raise your risk of heart problems and cancer, and too much vitamin D can cause your body to absorb too much calcium, which can be a serious medical emergency.

Yes, but make sure to talk to your provider before starting Dotremin (folic acid / cholecalciferol) to see if this supplement is right for you. It's recommended for pregnant women with low folic acid levels and low vitamin D levels to take a supplement like Dotremin (folic acid / cholecalciferol). Folic acid helps prevent anemia (low red blood cell count), and it's needed in pregnant women for healthy brain and spinal cord development in babies. Additionally, vitamin D helps build strong bones. But there might be other prenatal vitamins available that offer additional vitamin and mineral supplementation that are better suited for your particular needs.

The amount of time you need to take Dotremin (folic acid / cholecalciferol) will be different from person to person. Your provider might check your folic acid and vitamin D levels through blood work to see if you still need to take this medication. Don't stop this medication without having a conversation with your provider first.

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Risks and warnings for Dotremin (folic acid / cholecalciferol)

Dotremin (folic acid / cholecalciferol) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

Toxicity from taking too much

  • Risk factors: Taking more than the recommended dose

It's possible to take too much Dotremin (folic acid / cholecalciferol), which can cause serious side effects from either too much folic acid or too much vitamin D. Follow your healthcare provider's instructions for how to take this supplement properly. Since many over-the-counter supplements contain these vitamins, always check with your provider or pharmacist to make sure you're not taking too much. Let your provider know if you experience symptoms of too much vitamin D (e.g., nausea, vomiting, constipation, low appetite, increased thirst, urinating more frequently, unusual tiredness).

Potential to hide anemia due to low vitamin B12

Dotremin (folic acid / cholecalciferol) contains folic acid, which can sometimes mask a condition called pernicious anemia (a type of anemia due to low vitamin B12 levels). Avoid using this medication alone if you have low vitamin B12 levels. If you have a history of low vitamin B12 levels, let your healthcare provider know.

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Dotremin (folic acid / cholecalciferol) dosage

The average cost for 3 bottles of 30 tablets of 1700mcg/250mcg of Dotremin (folic acid / cholecalciferol) is $2,886.25 with a free GoodRx coupon.
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DosageQuantityPrice as low asPrice per unit
30 tablets of 1700mcg/250mcg3 bottles$2,886.25$962.08

Typical dosage for Dotremin (folic acid / cholecalciferol)

Brands may contain different amounts of folic acid and cholecalciferol (vitamin D3) and have different directions for use. Read the package label and prescription carefully to make sure you're taking the medication as directed by your provider. Below are some examples of folic acid-vitamin D products and their dosing.

  • Dotremin or Folditam: The typical dose is 1 tablet by mouth once per day. Each tablet contains 1 mg of folic acid and 250 mcg (or 10,000 international units, IU) of vitamin D3.

  • Folvite D: The typical dose is 1 tablet by mouth once or twice per day. Each tablet contains 1 mg of folic acid and 94.4 mcg (or 3,775 international units, IU) of vitamin D3.

Your provider will change the dose based on how your folic acid and vitamin D levels respond to the medication.

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Dotremin (folic acid / cholecalciferol) contraindications

Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Dotremin (folic acid / cholecalciferol) will not be safe for you to take.

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