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flurandrenolide

Generic Cordran
Used for Eczema, Psoriasis, Itching, Skin Allergy
Used for Eczema, Psoriasis, Itching, Skin Allergy

Flurandrenolide (Cordran) is a topical steroid medication used to relieve inflammation and itching caused by certain skin conditions in adults and children. It comes in various forms, including as a lotion, cream, and tape. The tape is available under the brand name Cordran Tape and is usually applied every 12 hours. Other forms are applied 2 to 3 times a day. Cordran Tape is considered ultra-high in potency (or very strong), while other forms are medium strength. Side effects can include burning, itching, and irritation at the application site.

Reviewed by:
reviewer
Kristianne Hannemann, PharmD
reviewer
Allison Gourley, PharmD
Last reviewed on September 17, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesReferencesPricesMedicare
basics-icon

What is Flurandrenolide (Cordran)?

What is Flurandrenolide (Cordran) used for?

  • Inflammatory and itchy skin conditions

How Flurandrenolide (Cordran) works

Flurandrenolide (Cordran) is a topical steroid. It blocks certain substances in the body that cause inflammation, which can lead to symptoms like swelling, redness, and itching. This helps treat flare-ups in certain skin conditions.

Drug Facts

Common BrandsCordran
Drug ClassCorticosteroid
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$518.31(save 88.57%)
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$59.22
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What are the side effects of Flurandrenolide (Cordran)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Burning
  • Itching
  • Irritation

Other Side Effects

  • Dryness
  • Inflamed hair follicles
  • Excess hair growth
  • Acne or pustules
  • Lighter skin color
  • Skin thinning
  • Stretch marks
  • Rash
  • Infection

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Blistering, burning, crusting, dryness, or flaking of the skin

irritation

itching, scaling, severe redness, soreness, or swelling of the skin

redness and scaling around the mouth

thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Acne or pimples

burning and itching of the skin with pinhead-sized red blisters

burning, itching, and pain in hairy areas, or pus at the root of the hair

increased hair growth on the forehead, back, arms, and legs

lightening of normal skin color

lightening of the treated areas of dark skin

reddish purple lines on the arms, face, legs, trunk, or groin

softening of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Flurandrenolide (Cordran)

thumbs-up

Pros

Treats various skin conditions that cause inflammation and itching

Few side effects if used for short periods of time

Comes in lotion, cream, and tape forms

Cordran Tape protects the medicated area from clothing and drying out

thumbs-down

Cons

Long-term use can lead to many side effects

Cream and lotion need to be applied up to 3 times a day

Can be used in adults and children

Cordran Tape is not available as a generic

pharmacist-tips

Pharmacist tips for Flurandrenolide (Cordran)

pharmacist

  • Before applying flurandrenolide (Cordran), make sure the affected areas of skin are clean and dry. Afterwards, wash your hands well to prevent the medication from getting in your eyes, unless your hands are areas being treated.

    • Shake the bottle of lotion well before using. If using the cream or lotion forms of flurandrenolide (Cordran), only apply the smallest amount needed to cover the affected areas of your skin. Be sure to rub it in gently and completely after applying.

      • Before using the Cordran Tape, shave or cut any hair in the affected area so that the tape sticks well. And cut a piece that's a little larger than the area you plan to cover. The tape is usually changed out every 12 hours, but if you don't experience irritation, you can leave it on for up to 24 hours.

        • Don't cover areas where flurandrenolide (Cordran) is applied with bandages or dressings unless instructed by your prescriber. If your child is using the medication in the diaper area, avoid tight-fitting diapers or plastic pants. Covering medicated areas can affect absorption and raise the risk of side effects.

          • If your prescriber recommended that you cover the area with bandages or dressings after applying flurandrenolide (Cordran), and you notice redness, itching, pain, or swelling, contact them. These could be signs of a skin infection.

            • Don't use flurandrenolide (Cordran) on your face, underarms, or groin areas unless directed by your prescriber.

              • Stop using flurandrenolide (Cordran) once your condition is under control. If you don't see improvement within 2 weeks, talk to your prescriber.

                • If you're using other corticosteroid products, check with your prescriber first before using flurandrenolide (Cordran). Using multiple corticosteroids raises your risk of side effects.

                  faqs

                  Frequently asked questions about Flurandrenolide (Cordran)

                  Does Cordran Tape expire?
                  Yes, Cordran Tape expires. Check for the expiration date on the package, or ask your pharmacist. Don't use the tape after the expiration date because it might not work as well.
                  How do you use Cordran Tape?
                  Before using Cordran Tape, gently clean the area on your skin where you'll apply it. Shave or trim any hair to help the tape stick. Cut a piece slightly larger than the affected area, remove the white paper, and press the tape onto your skin. Follow your prescriber's directions for how long to keep the tape on.
                  Is Cordran Tape still available?
                  Yes, Cordran Tape is still available. It isn't over the counter, so you'll need a prescription from a healthcare professional to use it.
                  Does Cordran Tape work for keloids?
                  There's some evidence that steroid tapes like Cordran can improve scars called keloids. Talk to your dermatologist before using this medication, so they can make sure it's the best treatment for you.
                  Is there a generic Cordran Tape?
                  No. Cordran Tape is currently only available as a brand name, and there isn't a generic version available.
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                  What are the risks and warnings for Flurandrenolide (Cordran)?

                  Flurandrenolide (Cordran) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                  risk-warning

                  Hormone problems and withdrawal

                  • Risk factors: Applying flurandrenolide (Cordran) to large areas of the body | Using flurandrenolide (Cordran) for a long time | Covering the medicated area | Children

                    It's possible for your body to absorb too much flurandrenolide (Cordran) through the skin in certain situations, like applying the medication to larger areas of skin over longer periods of time and covering the treated area with tight bandages. This can cause changes in your stress hormone levels (e.g., cortisol), affecting many bodily functions. Symptoms can include tiredness, nausea, and muscle aches, which usually go away after stopping the medication, though severe cases may require additional treatment. And very rarely, more serious problems related to having too much medication in the body can include having higher blood sugar levels and, in children, possibly delayed growth. So it's important to apply flurandrenolide (Cordran) only as directed by your prescriber.

                    risk-warning

                    Skin irritation

                    • Risk factors: Applying flurandrenolide (Cordran) to the folds of the skin or face

                      Unless instructed by your prescriber, don't apply flurandrenolide (Cordran) to the face. This medication can cause skin thinning and skin damage, even with short-term use. Apply the smallest amount needed for the shortest duration possible.

                      risk-warning

                      New or worsened skin infection

                      Flurandrenolide (Cordran) can lower your body's ability to fight infections, including infections on your skin. It's especially important to treat skin infections with an appropriate antifungal or antibacterial medication if you're using flurandrenolide (Cordran). The longer you're using this medication, the higher your risk of this problem. If you notice redness, pain, swelling, or pus where you are applying flurandrenolide (Cordran), stop using it and talk to your prescriber right away.

                      dosage

                      Flurandrenolide (Cordran) dosage forms

                      The average cost for 1 bottle of 120ml of 0.05% of Flurandrenolide (Cordran) is $59.22 with a free GoodRx coupon. This is 88.57% off the average retail price of $518.31.
                      bottle of lotion
                      Bottle of lotion
                      DosageQuantityPrice as low asPrice per unit
                      120ml of 0.05%1 bottle$59.22$59.22
                      tube of cream
                      Tube of cream
                      DosageQuantityPrice as low asPrice per unit
                      60g of 0.05%2 tubes$207.07$103.53
                      120g of 0.05%1 tube$301.15$301.15
                      tube of ointment
                      Tube of ointment
                      DosageQuantityPrice as low asPrice per unit
                      60g of 0.05%1 tube$134.52$134.52

                      Typical dosing for Flurandrenolide (Cordran)

                      • Cream and lotion: Apply a thin layer to the affected area(s) 2 or 3 times daily.

                      • Tape: Apply to the affected area(s) once or twice daily as directed by your prescriber.

                      interactions

                      Interactions between Flurandrenolide (Cordran) and other drugs

                      Flurandrenolide (Cordran) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Flurandrenolide (Cordran). Please note that only the generic name of each medication is listed below.

                      Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

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                      How much does Flurandrenolide (Cordran) cost?

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                      Cordran (brand)
                      GoodRx lowest price

                      $59.22

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                      Flurandrenolide (Cordran) (generic)
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                      $59.22

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                      contraindications-icon

                      Flurandrenolide (Cordran) contraindications

                      Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Flurandrenolide (Cordran) will not be safe for you to take.

                      • Skin folds or areas that rub up against each other (for Cordran Tape only)

                      • Wound or lesions that leak fluid (for Cordran Tape only)

                      alternatives

                      What are alternatives to Flurandrenolide (Cordran)?

                      There are a number of medications that your doctor can prescribe in place of Flurandrenolide (Cordran). Compare a few possible alternatives below.
                      Flurandrenolide (Cordran)
                      Used for:

                      • Inflammatory and itchy skin conditions

                      $59.22 Lowest GoodRx priceView Prices
                      Halcinonide (Halog)
                      Used for:

                      • Inflammatory and itchy skin conditions

                      $128.48 Lowest GoodRx priceView Prices
                      Halobetasol
                      Used for:

                      • Inflammatory skin conditions - cream and ointment only

                      • Plaque psoriasis - lotion and foam only

                      $29.37 Lowest GoodRx priceView Prices

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                      References

                      Best studies we found

                      Alexandraki, K. I., et al. (2018). Adrenal suppression. Endotext.

                      Almirall, LLC. (2023). Cordran- flurandrenolide cream; Cordran- flurandrenolide ointment [package insert]. DailyMed.

                      Almirall, LLC. (2023). Cordran- flurandrenolide tape [package insert]. DailyMed.

                      View All References (3)

                      National Psoriasis Foundation. (2022). Potency chart.

                      Ogawa, R. (2020). Chapter 56 Effectiveness of corticosteroid tapes and plasters for keloids and hypertrophic scars. Textbook on Scar Management: State of the Art Management and Emerging Technologies.

                      Padagis Israel Pharmaceuticals Ltd. (2022). Flurandrenolide- flurandrenolide lotion [package insert]. DailyMed.

                      GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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