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Fabrazyme

Fabrazyme Side Effects

Allison Gourley, PharmDRobert Chad Hakim, PharmD, BCCCP
Reviewed by Allison Gourley, PharmD, Robert Chad Hakim, PharmD, BCCCP
Last reviewed on January 5, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Upper respiratory tract infection (53%)
  • Chills (49%)
  • Fever (39%)
  • Headache (39%)
  • Cough (33%)
  • Feeling of "pins and needles" (31%)
  • Low energy (24%)
  • Swelling in arms, feet, or ankles (21%)
  • Dizziness (21%)
  • Rash (20%)
  • Arm or leg pain (19%)
  • Muscle pain (18%)
  • Lower respiratory tract infection (18%)
  • Back pain (16%)
  • High blood pressure (14%)
  • Itching (10%)

Less Common Side Effects

  • Fast heart rate
  • Chest discomfort
  • Shortness of breath
  • Wheezing
  • Ringing in the ears
  • Hearing problems
  • Burning sensation
  • Anxiety
  • Depression

Fabrazyme serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reaction (anaphylaxis): trouble breathing, tightness in the throat, hives, itching, fast heartbeat, nausea, stomach pain, dizziness, lightheadedness, swelling in the face or tongue

Source: DailyMed

The following Fabrazyme side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Blurred vision

chest pain, discomfort, or tightness

confusion

cough producing mucus

difficulty breathing

difficulty in moving

dizziness

faintness or lightheadedness when getting up suddenly from a lying or sitting position

feeling unusually cold shivering

headache

hives or welts, itching, skin rash

irregular heartbeat

joint pain

muscle ache, cramps, pains, or stiffness

nervousness

pounding in the ears

redness of the skin

stomach pain

sweating

swelling of the ankles, feet, and lower legs

swollen joints

unusual tiredness or weakness

Incidence unknown

Blue lips, fingernails, or skin

chills

cloudy or bloody urine

cough

decreased cardiac output

decreased frequency or amount of urine

difficulty in speaking

difficulty swallowing

dilated neck veins

double vision

feeling of constant movement of self or surroundings

fever

high blood pressure

inability to move the arms, legs, or facial muscles

increased thirst

irregular, fast, or slow, or shallow breathing

lack or loss of strength

loss of appetite

lower back or side pain

nausea

no breathing

no pulse or blood pressure

noisy breathing

pain in the joints

pain or discomfort in the arms, jaw, back, or neck

problems with muscle control or coordination

seizures

sensation of spinning

severe or sudden headache

shakiness and unsteady walk

slow or slurred speech

swollen, painful, or tender lymph glands in the neck, armpit, or groin

temporary blindness

throat tightness

trembling

trouble breathing

unconsciousness

vomiting

weakness in the arm and/or leg on one side of the body, sudden and severe

weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

Acid or sour stomach

belching

body aches or pain

body produces substance that can bind to drug making it less effective or cause side effects

burning, crawling, itching, numbness, prickling, "pins and needles" , or tingling feelings

congestion

discouragement

dryness or soreness of the throat

fear

feeling sad or empty

fever, not related to infusion

heartburn

hoarseness

indigestion

irritability

loss of interest or pleasure

pain or tenderness around eyes and cheekbones

paleness of skin

runny nose

sensation of change in temperature

skeletal pain

sneezing

stuffy nose

trouble concentrating

trouble sleeping

voice changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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