The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Adults and children 6 years or older:
- Rash (36%)
- Infusion reaction (32%)
- Upper respiratory tract infection (e.g., common cold; 32%)
- Flushing (23%)
- Injection site reaction (18%)
- Overactive reflexes (14%)
- "Pins and needles" feeling (14%)
Children 6 months to 5 years old:
- Infusion reaction (35%)
- Ear infection (20%)
Less Common Side Effects
- Injection site pain
- Chest pain
- Face swelling
- Swelling in lower part of the body
- Abscess (collection of pus)
- Scarring or clouding of the eye
- Low blood pressure
- Low platelet count
- High bilirubin levels
Aldurazyme serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe allergic reaction: slow heart rate, hives, breathing problems, swelling of the mouth or throat
- Sudden heart and lung problems: fast breathing, trouble breathing, swelling, change in heart rate, chest tightness or pain, blue skin color
Source: DailyMed
The following Aldurazyme side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Abdominal or stomach pain
accumulation of pus
back pain
black, tarry stools
bleeding gums
blood in urine or stools
blurred vision
chest tightness
chills
clay-colored stools
confusion
dark urine
dizziness
drowsiness
facial swelling
faintness
fast, pounding, or irregular heartbeat or pulse
flushing
headache
hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at injection site
lightheadedness when getting up from a lying or sitting position suddenly
loss of appetite
nausea or vomiting
pale skin
pinpoint red spots on skin
shortness of breath
skin rash
sweating
swollen, red, or tender area of infection
trouble breathing
unpleasant breath odor
unusual bleeding or bruising
unusual tiredness or weakness
vomiting of blood
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Bleeding, blistering, burning, coldness, or discoloration of skin
blindness
body aches or pain
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
decreased vision
difficulty in moving
ear congestion
feeling of pressure
loss of voice
muscle pain or stiffness
overactive reflexes
pain in joints
swelling of legs and feet
swelling or puffiness of face
varicose or spider veins
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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