Key takeaways:
Evenity (romosozumab-aqqg) is a reference (brand-name) osteoporosis injection that you receive once a month. The average retail cost of Evenity without insurance is $.
Evenity is a specialty medication that must be administered by a healthcare professional. You’ll need to use a specialty pharmacy to fill your prescription. In some cases, your prescriber may order Evenity to be shipped to their office.
If you have commercial insurance, you may be able to pay as little as $0 per dose for Evenity using a copay savings card. If you meet certain financial requirements, a patient assistance program may help you access Evenity for free.
Save on related medications
Osteoporosis is a common health condition, especially if you’ve completed menopause. Most people start with oral osteoporosis medications. But if you have a very high risk for fractures (bone breaks), you may need an injectable treatment. Evenity (romosozumab-aqqg) is an option your prescriber may recommend.
Evenity is a specialty medication. This means that only certain pharmacies can fill a prescription for it. It also means the medication is likely to have a higher cost. But how much is Evenity without insurance? And are there ways you can save on this osteoporosis injection?
How much does Evenity cost without insurance?
According to the manufacturer, the list price for Evenity is over $1,300 per syringe, as of January 2026. Retail prices are typically higher than the list price because of pharmacy and wholesaler markups.
The average retail cost of Evenity without insurance is $. But if you have insurance, you’d usually pay less than this.
Evenity comes as a 105 mg / 1.17 mL injection. You’ll receive 2 injections on the same day once a month, administered by a healthcare professional in their office or clinic. Evenity is a reference (brand-name) biologic. It doesn’t have a biosimilar (generic) version available.
Which factors affect the cost of Evenity?
Several factors can affect how much you pay for Evenity. Some factors can increase costs, while others may decrease it.
Reference vs. biosimilar availability
Reference biologics are typically more costly than biosimilar versions. Because Evenity doesn’t have a biosimilar, its price is higher. When a biosimilar becomes available, costs are expected to go down.
Location
Medications can cost different amounts depending on where you live. For example, people in Denver tend to pay less for prescriptions overall than people in New Orleans.
Pharmacy
Only specialty pharmacies can fill prescriptions for Evenity. Unlike with nonspecialty medications, you can’t shop around to find the lowest Evenity price among pharmacies. Typically, your insurance plan will require you to use a particular specialty pharmacy.
Good to know: Your prescriber may order Evenity to be shipped to their office instead of going through a specialty pharmacy. This decision will likely depend on your insurance plan’s requirements.
Insurance coverage and discounts
The cost of Evenity will likely be lower if you have insurance or use a manufacturer discount. But keep in mind that the price you pay may change over time. Insurance plans can charge different copays or coinsurance, depending on whether you’ve met your annual deductible or out-of-pocket maximum.
Review your plan’s summary of benefits and coverage and formulary (list of covered medications). This can help you determine if your plan covers Evenity. If you’re unsure, you can also call the member services phone number on your prescription insurance card.
What to do if Evenity isn’t covered by your insurance
If your insurance doesn’t cover Evenity, try these options:
Check to see if you’re eligible for Evenity’s patient assistance program (more on this below).
Request a formulary exception from your insurance company. If your request is denied, you have the right to appeal the decision to seek coverage.
Discuss alternative osteoporosis medications, such as Prolia (denosumab), with your prescriber. Many have lower-cost generic or biosimilar versions available or may be preferred by your insurance provider.
When it’s time for open enrollment, compare different health insurance plans to find one that provides better coverage for the medications you need.
Ways to save on Evenity
Regardless of your insurance status, there are ways to save on Evenity. Here are four options to consider.
Good to know: If you’re receiving Evenity through a specialty pharmacy, a pharmacist can help you apply for savings opportunities.
1. See if you qualify for a copay savings card
If you have commercial insurance that covers Evenity, you may pay as little as $0 per dose with a manufacturer copay card.
To be eligible for the copay card, you must:
Have commercial insurance that pays for part of your Evenity prescription
Not have government-funded insurance, such as Medicare, Medicaid, or Tricare
Have a valid prescription for Evenity
Live in the U.S. or a U.S. territory
This program is not available for people who are uninsured or whose commercial plan doesn’t cover Evenity. You can sign up for the copay card online. For questions about the program or your eligibility, call 1-866-264-2778.
2. Check if you’re eligible for the manufacturer’s patient assistance program
If you’re uninsured or underinsured, you may be able to access Evenity for free through the Amgen Safety Net Foundation. This is the manufacturer’s patient assistance program. If you meet certain financial requirements, this program can provide Evenity for you at no cost.
To qualify for the Amgen Safety Net Foundation, you must:
Have no insurance, or have Medicare and be unable to afford your medication
Have lived in the U.S. or a U.S. territory for at least 6 months
Meet certain income requirements and be able to submit proof of income
To see if you’re eligible or to start the application process, call 1-866-264-2778.
3. Check if you’re eligible for independent patient assistance programs
Evenity’s manufacturer isn’t the only one that offers a patient assistance program. Several nonprofit organizations also provide financial assistance for people who meet certain criteria.
Consider checking out the following independent patient assistance programs to see if you qualify:
Each program has its own eligibility criteria. If a program isn’t accepting new applicants, you may be able to join a waitlist to be notified when enrollment is open again.
4. Tap into your HSA, FSA, or HRA
Consider using a health savings account (HSA), flexible spending account (FSA), or health reimbursement arrangement (HRA) to purchase Evenity. These accounts let you use pretax dollars to pay for copays, coinsurances, and other qualified medical expenses. This can help you save money through tax savings.
Just be sure to review your account’s details regarding expiration dates. FSA dollars have an expiration date. But HSA funds roll over and can be saved for later. HRAs may or may not expire, depending on your account.
The bottom line
Evenity (romosozumab-aqqg) is a reference (brand-name), once-monthly osteoporosis injection. The average retail cost of Evenity without insurance is $. Using your insurance is the best way to help reduce the cost. Evenity is a specialty medication. So you can get the medication only from specialty pharmacies or at your prescriber’s office.
If you have commercial insurance, you may be able to pay as little as $0 per dose for Evenity using a manufacturer copay card. If you’re uninsured or underinsured, you may qualify for Evenity’s patient assistance program. This program offers the medication for free to people who meet certain financial requirements.
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References
Amgen. (n.d.). Paying for Evenity.
Amgen. (2026). Evenity- romosozumab-aqqg injection, solution [package insert]. DailyMed.
Amgen. (2026). Evenity- romosozumab-aqqg list pricing.
Amgen Safety Net Foundation. (n.d.). Eligibility.
Amgen Support. (n.d.). Co-pay program.
Endocrine Society. (2022). Menopause and bone loss.
HealthWell Foundation. (n.d.). Post menopausal osteoporosis - Medicare access.
Patient Advocate Foundation. (n.d.). Osteoporosis.
