Butalbital/acetaminophen/caffeine (Esgic, Floricet, Phrenilin Forte, Zebutal) is an inexpensive drug used to treat tension headaches. It is more popular than comparable drugs. it is available in multiple generic and brand versions. Generic butalbital/acetaminophen/caffeine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.