The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Involuntary movements (dyskinesia, 25%)
- Nausea (14%)
- Muscle spasms (hyperkinesia, 10%)
- Changes in the color of your urine (10%)
- Diarrhea (10%)
- Slowed muscle movements (hypokinesia, 9%)
- Stomach pain (8%)
- Dizziness (8%)
Less Common Side Effects
- Back pain
- Vomiting
- Constipation
- Dry mouth
- Tiredness
- Shortness of breath
Entacapone serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Neuroleptic malignant syndrome (NMS): very high fevers, irregular pulse, sweating, muscle stiffness, confusion
- Severe muscle damage (rhabdomyolysis): muscle aches, soreness, cramping, dark-colored urine, weakness
Source: DailyMed
The following Entacapone side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Absence of or decrease in body movements
hyperactivity
increase in body movements
seeing, hearing, or feeling things that are not there
twisting
twitching
uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Acid or sour stomach
belching
bruising
burning feeling in the chest or stomach
difficult or labored breathing
indigestion
irritability
loss of strength or energy
muscle pain or weakness
passing gas
restlessness
sleepiness or unusual drowsiness
small, red spots on the skin
stomach discomfort, upset, or tenderness
sweating increased
tightness in the chest
trouble sleeping
unusual or unpleasant (after) taste
unusual weak feeling
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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