Durysta
Durysta (bimatoprost) lowers eye pressure for people with high eye pressure or open-angle glaucoma. It's a dissolvable implant that must be placed by a healthcare provider and can be expensive.
What is Durysta (bimatoprost)?
What is Durysta (bimatoprost) used for?
Open-angle glaucoma
High pressure in the eye (ocular hypertension)
How Durysta (bimatoprost) works
Durysta (bimatoprost) is a prostaglandin. It helps fluid drain from inside the eye, which lowers eye pressure.
Drug Facts
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What are the side effects of Durysta (bimatoprost)?
Common Side Effects
- Eye redness (27%)
- Feeling like there's something in your eye (5-10%)
- Eye pain (5-10%)
- Sensitivity to light (5-10%)
- Blood spot on the white of your eye (5-10%)
- Dry eye (5-10%)
- Eye irritation (5-10%)
- Higher eye pressure (5-10%)
- Blurry vision (5-10%)
- Iris inflammation (swelling, 5-10%)
- Headache (5%)
Other Side Effects
- Watery eyes
- General eye discomfort
- Browning of your eye color
- Eye inflammation and swelling
Serious Side Effects
- Eye infection (endophthalmitis): red eyes, sensitivity to light, eye pain, change in vision
Source: FDA
The following side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Change in vision
- New or worsening eye pain, redness, irritation, or discharge
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
- Change in eye color
- Dry eyes
- Eye irritation or itching
- Increased tears after use
Pros and cons of Durysta (bimatoprost)
Pros
One implant lasts for many months
No need to remember to use daily eye drops
Manufacturer provides a copay assistance card
Cons
Implant requires a procedure given by a healthcare provider
Should only be used once (per eye) in your lifetime
Can change the color of your eye
Pharmacist tips for Durysta (bimatoprost)
Let your provider know if you've ever had a Durysta (bimatoprost) implant before. Each eye should only get one implant.
Make sure your provider has your whole medical and surgical history. Durysta (bimatoprost) is not for everyone.
Darkening eye color is a common side effect. This color change isn't harmful, but it can be permanent. Let your provider know beforehand if this is a concern for you.
Frequently asked questions about Durysta (bimatoprost)
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What are the risks and warnings for Durysta (bimatoprost)?
Durysta (bimatoprost) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
One-time use due to eye-related side effects
Risk factors: History of cornea cell loss
Durysta (bimatoprost) can cause a lot of side effects related to your cornea (the clear, protective, outer layer of the eye). It should not be used if you have a history of cornea cell breakdown. Because of this risk, each eye should only have one Durysta (bimatoprost) implant placed in your lifetime.
Eye inflammation and swelling
Risk factors: Eye inflammation, such as with uveitis | Missing or injured eye lens
Prostaglandins like Durysta (bimatoprost) can cause or worsen eye inflammation (swelling). Durysta (bimatoprost) can also cause macular edema, or swelling of the macula (a part of the eye that's important for clear vision). Both of these problems are more likely to happen if you already have eye inflammation or if the lens of your eye is damaged or missing. Talk to your provider immediately if you notice eye discomfort or changes in your vision while using Durysta (bimatoprost).
Darker eyes, eyelids, or eyelashes
Risk factors: Long-term use of Durysta (bimatoprost)
Prostaglandin eye drops like Durysta (bimatoprost) can darken the color of your eyes. Darkening color of the eye is usually more noticeable after a few months of using Durysta (bimatoprost) and can be permanent. These side effects are not known to be harmful, but it's best to check in with your provider regularly so they can make sure your eyes stay healthy.
Durysta (bimatoprost) dosage forms
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 10mcg | 1 implant | $2004.60 | $2004.60 |
Typical dosing for Durysta (bimatoprost)
Durysta (bimatoprost) is a dissolvable implant that contains 10 mcg of medication. It's placed in the affected eye(s) by a healthcare provider as a one-time procedure. The implant releases medication into your eye over time.
How much does Durysta (bimatoprost) cost?
Durysta (bimatoprost) contraindications
Eye infection
Cornea cell loss or breakdown (corneal endothelial cell dystrophy)
History of cornea transplant
Ruptured posterior lens or a lack of one
What are alternatives to Durysta (bimatoprost)?
Open-angle glaucoma
High pressure in the eye (ocular hypertension)
High pressure in the eye caused by ocular hypertension (high pressure inside the eye) or open-angle glaucoma (the most common type of glaucoma)
Lowering pressure in the eye in people with open-angle glaucoma or ocular hypertension (high pressure in the eye)
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