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Duopa

Duopa Dosage

Kristianne Hannemann, PharmDCydnee Ng, PharmD
Reviewed by Kristianne Hannemann, PharmD, Cydnee Ng, PharmD
Last reviewed on April 8, 2026

Typical dosage for Duopa

Before you can start Duopa, you need to be taking a stable dose of immediate-release carbidopa / levodopa (Sinemet) first.

When you switch to Duopa, your dose will depend on the total amount of carbidopa/levodopa you usually take per day.

Duopa is given using a pump that sends the medication into your intestine through a PEG-J tube. The infusion pump is set up for your specific treatment plan.

In general, there are three parts to each infusion:

  1. A morning dose that's given over 10 to 30 minutes
  2. A continuous dose that's infused over 16 hours
  3. Extra doses as needed (no more than every 2 hours)

Your prescriber might adjust your dose depending on how the medication is working for you.

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