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Duloxicaine

Duloxicaine Side Effects

Ally Tsai, PharmDAllison Gourley, PharmD
Reviewed by Ally Tsai, PharmD, Allison Gourley, PharmD
Last reviewed on March 31, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Duloxetine 30 mg capsule

  • Nausea (23%)
  • Headache (14%)
  • Dry mouth (13%)
  • Drowsiness (10%)
  • Feeling tired (9%)
  • Trouble sleeping (9%)
  • Dizziness (9%)
  • Constipation (9%)
  • Diarrhea (9%)

Lidocaine 4% cream

Less Common Side Effects

Duloxetine 30 mg capsule

  • Low appetite
  • Belly pain
  • Indigestion
  • Trouble urinating
  • Upper respiratory tract infections (e.g., runny or stuffy nose, sore throat, cough)
  • Tingling sensation
  • Feeling agitated or distressed
  • Excessive sweating
  • Flushing
  • Racing heart
  • Low sex drive

Duloxicaine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Suicidal thoughts or behaviors
  • Serotonin syndrome: high fever, sweating, fast heartbeat, muscle spasms, tremors, restlessness, confusion
  • Liver damage: loss of appetite, severe stomach pain, yellowing of skin or eyes
  • Severe skin reaction: blisters, peeling rash, sores
  • Blood problems (methemoglobinemia): skin color turning blue; anxiety; feeling dizzy, faint, or tired; fast heartbeat; trouble breathing
  • Too much lidocaine absorbed through the skin: lightheaded, dizzy, difficulty controlling muscle movements

Source: DailyMed

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