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Dronabinol

Dronabinol Side Effects

Robert Chad Hakim, PharmD, BCCCPCydnee Ng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Cydnee Ng, PharmD
Last reviewed on September 12, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Dizziness (up to 10%)
  • Sleepiness (up to 10%)
  • Euphoria (e.g., feeling "high," easy laughing, happiness; up to 10%)
  • Paranoia (intense anxiety or fearful thoughts; up to 10%)
  • Abnormal thinking (up to 10%)
  • Stomach pain (up to 10%)
  • Nausea (up to 10%)
  • Vomiting (up to 10%)

Less Common Side Effects

  • Weakness
  • Confusion
  • Anxiety or nervousness
  • Coordination problems
  • Slurred speech
  • Hallucination (seeing or hearing things that aren't there)
  • Problems remembering
  • Fast heartbeat
  • Flushing

Dronabinol serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Worsening mental health: depression, manic episode, schizophrenia
  • Changes in blood pressure
  • Seizures
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When do Dronabinol possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Dizziness
Euphoria
Abnormal thinking

Source: DailyMed

The following Dronabinol side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Changes in mood

confusion

delusions

fast or pounding heartbeat

feelings of unreality

loss of memory

mental depression

nervousness or anxiety

problems with memory

seeing, hearing, or feeling things that are not there

Rare

Blurred vision

chills

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

sweating

unusual tiredness or weakness

Incidence not known

Fainting

feeling of warmth

hives or rash

redness of the face, neck, arms, and occasionally, upper chest

seizures

sores in the mouth

swelling of the lips

tightness in the throat

trouble sleeping

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Being forgetful

change in how fast you think time is passing

change in your sense of smell, taste, sight, sound, or touch

constipation

decrease in motor coordination

drowsiness (severe)

dryness of the mouth (severe)

false sense of well-being

feeling sluggish

panic reaction

problems in urinating

redness of the eyes

seizures

slurred speech

unusual drowsiness or dullness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Clumsiness or unsteadiness

dizziness

drowsiness

false sense of well-being

nausea

trouble with thinking

vomiting

Less common or rare

Abdominal or stomach pain

flushing of the face

lack or loss of strength

restlessness

Rare

Burning, dry, or itching eyes

continuing ringing or buzzing or other unexplained noise in the ears

cough

diarrhea

discharge, excessive tearing

headache

hearing loss

redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid

runny nose

sneezing

stuffy nose

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.

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