The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Changes in heart rate
- Nausea
- Vomiting
- Diarrhea
- Reduced appetite
Less Common Side Effects
- Headache
- Weakness
- Dizziness
- Confusion
- Rash
- Enlarged male breasts
Digoxin serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Abnormal heart rhythm: chest pain, chest discomfort, palpitations, shortness of breath, fatigue, weakness, sweating
- Digoxin toxicity: nausea, vomiting, loss of appetite, changes in vision, confusion, palpitations, or abnormally slow heart rate
Source: DailyMed
More on Digoxin side effects

5 Digoxin Side Effects That You Should Know About
Written by Sarah Lobello Pearson, PharmD
The following Digoxin side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Digoxin toxicity—confusion, loss of appetite, nausea, vomiting, diarrhea, change in vision such as blurry or yellow vision, fatigue, fast or irregular heartbeat
- Slow heartbeat—dizziness, feeling faint or lightheaded, confusion, trouble breathing, unusual weakness or fatigue
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Dizziness
- Stomach pain
- Unexpected breast tissue growth








