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02:15

Medications for Depression: How Long Does It Take to Find Relief?

You may have to be patient when starting an antidepressant for major depressive disorder.

Lauren Smith, MAMera Goodman, MD, FAAP
Written by Lauren Smith, MA | Reviewed by Mera Goodman, MD, FAAP
Published on July 31, 2023

Some people struggle with symptoms of major depressive disorder for months or years before seeking treatment. As a result, they may be very eager to see results when starting medication for depression.

Some people may see improvements within a few days, but others may need to wait several weeks to know if the medication is working, according to Jacques Ambrose, MD, MPH, FAPA, Psychiatrist at Columbia University Irving Medical Center.

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Additional Medical Contributors
  • Jacques Ambrose, MD, MPH, FAPAJacques Ambrose, MD, MPH, FAPA, is a Psychiatrist at Columbia University Irving Medical Center.

    References

    American Psychological Association. (n.d.). APA dictionary of psychology: Inpatient.

    Chand, S. P., et al. (2023). Depression. StatPearls.

    View All References (3)

    National Institute of Mental Health. (2023). Depression.

    Rush, A. J. (2023). Patient education: Depression treatment options for adults (beyond the basics). UpToDate.

    Rush, A. J. (2023). Unipolar major depression in adults: Choosing initial treatment. UpToDate.

    GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

    For additional resources or to connect with mental health services in your area, call SAMHSA’s National Helpline at 1-800-662-4357. For immediate assistance, call the National Suicide Prevention Lifeline at 988, or text HOME to 741-741 to reach the Crisis Text Line.

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